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Merck
CN

D-019

二氢可待因盐酸盐标准液 盐酸盐 溶液

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式（希尔记法）:
C18H23NO3·HCl
化学文摘社编号:
36418-29-8
分子量:
337.84
NACRES:
NA.24
PubChem Substance ID:
329798591
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00190607

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InChI key

VMZXMTVGOAQUEN-FFHNEAJVSA-N

InChI

1S/C18H23NO3.ClH/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;/h3,6,11-13,17,20H,4-5,7-9H2,1-2H3;1H/t11-,12+,13-,17-,18-;/m0./s1

SMILES string

Cl.COc1ccc2C[C@@H]3[C@@H]4CC[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

Quality Level

300

相关类别

General description

A Certified Snap-N-Spike® Solution suited for use as starting material in calibrators and controls for a variety of LC/MS or GC/MS applications from urine drug testing and pain prescription monitoring to forensic analysis and pharmaceutical research. Dihydrocodeine is an opioid analgesic developed for treatment of moderate to severe pain and as an antitussive.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

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Cautious advice.
Lieselotte Windhövel
Deutsches Arzteblatt international, 106(4), 57-57 (2009-07-01)
Erythema multiforme major putatively induced by dihydrocodeine phosphate.
Y Matsuzawa et al.
Clinical and experimental dermatology, 35(6), 673-674 (2010-03-30)
A I Al-Asmari et al.
Journal of analytical toxicology, 34(8), 476-490 (2010-01-01)
The focus of this study was to report the blood and urine concentrations of dihydrocodeine (DHC) and its metabolites, dihydrocodeine-6-glucuronide (DHC6G), dihydromorphine (DHM), dihydromorphine-3-glucuronide (DHM3G), and dihydromorphine-6-glucuronide (DHM6G) in deaths involving DHC, and to report the range of concentrations detected
Wojciech Leppert et al.
Current pharmaceutical biotechnology, 12(2), 306-312 (2010-11-06)
To assess tramadol and O-desmethyltramadol (M1) concentrations and their correlations with analgesia in patients with cancer pain. Thirty opioid-naive patients with nociceptive pain intensity on VAS (visual analogue scale) > 40 received controlled-release tramadol as the first (15 patients, 7
K Imhof et al.
Der Anaesthesist, 61(9), 815-819 (2012-09-12)
Patient-controlled analgesia (PCA) is an established standard therapy for providing postoperative analgesia. To avoid possible abuse by patients each PCA pump is secured by a pin code that should be neither known nor accessible to patients. The two case reports
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