D-047
N-去甲基西酞普兰盐酸盐 盐酸盐 溶液
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
别名:
N-去甲基西酞普兰盐酸盐 盐酸盐 溶液
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关于此项目
经验公式（希尔记法）:
C19H19FN2O · HCl
化学文摘社编号:
分子量:
346.83
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
SMILES string
Fc1ccc(cc1)[C@@]2(OCc3c2ccc(c3)C#N)CCCNC
InChI
1S/C19H19FN2O/c1-22-10-2-9-19(16-4-6-17(20)7-5-16)18-8-3-14(12-21)11-15(18)13-23-19/h3-8,11,22H,2,9-10,13H2,1H3/t19-/m0/s1
InChI key
PTJADDMMFYXMMG-IBGZPJMESA-N
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol (as free base)
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
Quality Level
General description
N-去甲基西酞普兰是SSRI抗抑郁药西酞普兰的一种活性代谢产物。西酞普兰在美国和加拿大以Celexa®的名义进行销售，可用于治疗与情绪障碍相关的重度抑郁症。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Celexa is a registered trademark of H. Lundbeck A/S
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
危险化学品
此项目有
Francesca-Maria Raffaelli et al.
Scientific reports, 10(1), 20203-20203 (2020-11-21)
Brown adipose tissue (BAT) thermogenesis is considered a potential target for treatment of obesity and diabetes. In vitro data suggest dopamine receptor signaling as a promising approach; however, the biological relevance of dopamine receptors in the direct activation of BAT
Lili Aslostovar et al.
Cell reports. Medicine, 2(2), 100202-100202 (2021-03-06)
The aberrant expression of dopamine receptors (DRDs) in acute myeloid leukemia (AML) cells has encouraged the repurposing of DRD antagonists such as thioridazine (TDZ) as anti-leukemic agents. Here, we access patient cells from a Phase I dose escalation trial to
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