D-920
N-去甲基三甲丙咪嗪标准液 溶液
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
别名:
N-Desmethyltrimipramine maleate solution
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关于此项目
经验公式（希尔记法）:
C19H24N2 · C4H4O4
CAS Number:
分子量:
396.48
EC 号:
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24
等级
certified reference material
质量水平
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol (as free base)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
包装形式
single component solution
储存温度
2-8°C
一般描述
N-Desmethyltrimipramine is a primary blood metabolite of trimipramine. Trimipramine is a tricyclic antidepressant prescribed for treatment of depression, insomnia, and chronic pain or as an adjunctive therapy for alcohol or opioid withdrawal. This Certified Snap-N-Spike® Solution is applicable for use in LC/MS or GC/MS applications for pain prescription monitoring, urine drug testing, clinical toxicology, and forensic analysis.
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
49.5 °F - closed cup
闪点(°C)
9.7 °C - closed cup
法规信息
危险化学品
J Liu et al.
Journal of chromatography. B, Biomedical sciences and applications, 700(1-2), 175-182 (1997-12-09)
A sensitive and stereospecific method for the quantitation of trimipramine enantiomers in human serum was developed. The assay involves the use of a novel mixed-mode disc solid-phase extraction for serum sample clean-up prior to HPLC analysis and is also free
A A Gulaid et al.
Journal of chromatography, 566(1), 228-233 (1991-05-03)
Trimipramine is a tricyclic antidepressant drug often assayed by gas chromatographic or gas chromatographic-mass spectrometry techniques. A high-performance liquid chromatographic method with electrochemical detection is described for the assay of trimipramine and its major metabolites, monodesmethyltrimipramine and 2-hydroxytrimipramine, in plasma.
J Degen et al.
Medizinische Klinik (Munich, Germany : 1983), 88(3), 129-133 (1993-03-15)
The pharmacokinetics of the antidepressants amitriptyline oxide and trimipramine and their major metabolites amitriptyline, nor-triptyline and desmethyltrimipramine, were studied in twelve healthy male subjects (aged from 22 to 62 years) and twelve patients (aged from 25 to 73 years) with
In vitro metabolism of desmethyltrimipramine to yield hydroxylamino compound.
S Ozkirimli et al.
Acta pharmaceutica Suecica, 23(1), 57-59 (1986-01-01)
A D Fraser et al.
Journal of analytical toxicology, 11(4), 168-170 (1987-07-01)
A fatality following ingestion of the tricyclic antidepressant trimipramine (Surmontil) is described. Quantitation was performed by high-performance liquid chromatography. Trimipramine and desmethyltrimipramine concentrations were 4.8 and 2.1 mg/L, respectively, in postmortem blood. The concentration of trimipramine, desmethyltrimipramine, and their respective
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