推荐产品
等级
certified reference material
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in acetonitrile
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
clinical testing
格式
single component solution
储存温度
2-8°C
SMILES字符串
CC12CCC3C(CCc4cc(O)ccc34)C1CCC2O
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChI key
VOXZDWNPVJITMN-ZBRFXRBCSA-N
基因信息
human ... ESR1(2099)
一般描述
认证加标溶液®，适合用作校准品、质控品或线性标准品的起始物料，用于从内分泌学到临床和诊断检测的各种LC/MS或GC/MS应用。
17β-雌二醇属于内源性内分泌干扰物，可干扰甲状腺活性和功能。它也是一种性激素，以商品名 Vagifem®，Estring®，Evamist，Elestrin®，Estrace®和 Estrogel® 开处方，可治疗雌激素过少症。
17β-雌二醇属于内源性内分泌干扰物，可干扰甲状腺活性和功能。它也是一种性激素，以商品名 Vagifem®，Estring®，Evamist，Elestrin®，Estrace®和 Estrogel® 开处方，可治疗雌激素过少症。
应用
该认证标准物质（CRM）还可作如下用途：
- 利用还原氧化石墨烯和金属络合卟啉传感器电化学测定河水样品中的 17β-雌二醇
- 开发基于荧光共振能量转移（FRET）的适配体传感器以测定环境水、尿液和牛奶样品中的 17β-雌二醇
- 使用石墨烯/多壁碳纳米管（MWCNT）进行固相萃取后，通过高效液相色谱（HPLC）结合荧光检测分析乳制品样品以估计 17β-雌二醇
- 使用磁性氧化石墨烯 (GO)/γ-Fe2O3 纳米颗粒，通过高效液相色谱（HPLC）结合荧光检测器进行定量分析，从自来水样品中固相萃取 17β-雌二醇和 17α-乙炔雌二醇
- 使用悬垂汞滴电极和丝网印刷碳电极对商业制剂和尿液样品中的 17β-雌二醇和 17α-乙炔雌二醇进行多残留分析
特点和优势
- 完全符合 ISO/IEC 17025 和 ISO 17034 认证
- 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
- 通过实时稳定性研究严格测试，以确保准确性和保质期
- 使用合格的精密天平进行重量准备，以确保最小不确定性
- 氩气环境下火焰密封，装入安瓿以便长期保存
- 提供方便的 DEA 豁免格式，以提高实验室效率
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Elestrin is a registered trademark of Azur Pharma
Estrace is a registered trademark of Warner Chilcott Company, LLC
Estring is a registered trademark of Pfizer Health AB
Estrogel is a registered trademark of Ascend Therapeutics, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vagifem is a registered trademark of Novo Nordisk A/S Corp.
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
35.6 °F - closed cup
闪点(°C)
2 °C - closed cup
法规信息
危险化学品
Hirotaka Ishii et al.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 13(4), 323-334 (2007-07-24)
It is believed that sex hormones are synthesized in the gonads and reach the brain via the blood circulation. In contrast with this view, the authors have demonstrated that sex hormones are also synthesized locally in the hippocampus and that
William Rosner et al.
The Journal of clinical endocrinology and metabolism, 98(4), 1376-1387 (2013-03-07)
The objective of the study was to evaluate the current state of clinical assays for estradiol in the context of their applications. The participants were appointed by the Council of The Endocrine Society and charged with attaining the objective using
Mark A Tarnopolsky
Medicine and science in sports and exercise, 40(4), 648-654 (2008-03-05)
Women oxidize more lipid and less carbohydrate and protein compared with men during endurance exercise. The increase in fat oxidation is associated with higher intramyocellular lipid content and use as well as greater adipocyte lipolysis. Glucose rates of appearance and
Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions.
S Safe
Vitamins and hormones, 62, 231-252 (2001-05-11)
Estrogen receptor-alpha (ER alpha) is a ligand-activated transcription factor and a member of the nuclear receptor superfamily. The classic mechanism of ER alpha action is associated with estrogen-induced formation of a nuclear ER alpha homodimer, binding to 5'-regulatory estrogen response
Michael J Gibney et al.
The American journal of clinical nutrition, 82(3), 497-503 (2005-09-13)
Metabolomics has been widely adopted in pharmacology and toxicology but is relatively new in human nutrition. The ultimate goal, to understand the effects of exogenous compounds on human metabolic regulation, is similar in all 3 fields. However, the application of
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