InChI
1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1
SMILES string
CC12CCC3C(CCc4cc(O)ccc34)C1CCC2=O
InChI key
DNXHEGUUPJUMQT-CBZIJGRNSA-N
grade
certified reference material
Quality Level
Gene Information
human ... ESR1(2099)
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
format
single component solution
storage temp.
−20°C
General description
通过LC-MS/MS或GC/MS监测血清或血浆中雌二醇,雌酮的前体,以评估和诊断女性的发育异常,酶失活或缺乏,多囊卵巢综合征(PCOS)或激素替代疗法。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
危险化学品
此项目有
Ghada N Farhat et al.
Journal of the National Cancer Institute, 105(19), 1496-1503 (2013-09-18)
Although high endogenous sex hormone levels and estrogen plus progestin (E+P) therapy are associated with increased breast cancer risk, it is unknown whether pretreatment levels of sex hormones modify E+P effect on breast cancer. We conducted a nested case-control study
Xavier Remesar et al.
Medicinal research reviews, 32(6), 1263-1291 (2011-02-03)
Oleoyl-estrone (OE) is a powerful slimming agent that is also present in plasma and adipose tissue, where it is synthesized. It acts through the formation of a derivative W. OE effects (and W levels) are proportional to the dose. OE
Eva Fetter et al.
Aquatic toxicology (Amsterdam, Netherlands), 154, 221-229 (2014-06-14)
Xenoestrogens may persist in the environment by binding to sediments or suspended particulate matter serving as long-term reservoir and source of exposure, particularly for organisms living in or in contact with sediments. In this study, we present for the first
Yoko Urata et al.
The Journal of clinical endocrinology and metabolism, 98(4), 1583-1590 (2013-03-02)
Endometriosis is a chronic inflammatory disease in which immune response and production of estrogen in endometriotic tissues are involved in the development of the disease. Prostaglandin E2 (PGE2) stimulates aromatase (P450arom) expression in endometrioma stromal cells (ESCs) and increases the
Kiyoshi Ito
The Tohoku journal of experimental medicine, 212(1), 1-12 (2007-04-28)
Hormone replacement therapy (HRT) has become available over the past few decades, but the risk of breast cancer with HRT remains controversial. The Women's Health Initiative Study has recently demonstrated that women receiving estrogen plus progestin (HRT) have an increased
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