ERP-109S
季戊四醇四硝酸酯 溶液
10 mg/mL in acetonitrile, ampule of 5 mL, certified reference material, Cerilliant®
别名:
Pentaerythritol tetranitrate, PETN
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关于此项目
经验公式（希尔记法）:
C5H8N4O12
化学文摘社编号:
分子量:
316.14
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
InChI
1S/C5H8N4O12/c10-6(11)18-1-5(2-19-7(12)13,3-20-8(14)15)4-21-9(16)17/h1-4H2
SMILES string
O=[N+]([O-])OCC(CO[N+]([O-])=O)(CO[N+]([O-])=O)CO[N+]([O-])=O
InChI key
TZRXHJWUDPFEEY-UHFFFAOYSA-N
grade
certified reference material
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 5 mL
manufacturer/tradename
Cerilliant®
concentration
10 mg/mL in acetonitrile
application(s)
environmental
format
single component solution
storage temp.
−20°C
Quality Level
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Application
- Chromatographic Analysis of Pentaerythritol Tetranitrate: A study developed a liquid chromatographic-mass spectrometric method for analyzing pentaerythritol tetranitrate metabolites, validating its application in both ovine serum and human plasma samples. This research supports the use of pentaerythritol tetranitrate in cardiovascular studies, enhancing drug metabolism research and pharmacokinetic profiling (Städtler et al., 2024).
- Biomedical Applications of Block Copolymers: Research explored the block sequence effects on the self-assembly behaviors of polypeptide-based penta-block copolymer hydrogels. While not directly about pentaerythritol tetranitrate, the study emphasizes the potential of similar nitrate compounds in developing pharmaceutical hydrogels and drug delivery systems, showcasing innovative materials in pharmacological research (Wang et al., 2024).
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
flash_point_f
35.6 °F - closed cup
flash_point_c
2 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
Xin Zhang et al.
Journal of colloid and interface science, 387(1), 175-179 (2012-09-15)
A simple technique for patterning organic materials using a surfactant assisted lift-off method is proposed. Thin films of various organic materials are prepared, and areas in contact with a surfactant coated poly(dimethylsiloxane) (PDMS) stamp are selectively removed. The general applicability
A Edtbauer et al.
The Journal of chemical physics, 132(13), 134305-134305 (2010-04-15)
Gas phase dissociative electron attachment (DEA) measurements to pentaerythritol tetranitrate (PETN) are performed in a crossed electron-molecular beam experiment at high-energy resolution and high sensitivity. DEA is operative at very low energies close to approximately 0 eV showing unique features
[Options of NO substitution: proven and future methods. A pharmaceutical classic on the upswing].
MMW Fortschritte der Medizin, 153(24-25), 50-51 (2011-07-02)
Swenja Schuhmacher et al.
Hypertension (Dallas, Tex. : 1979), 55(4), 897-904 (2010-02-17)
The organic nitrate pentaerythritol tetranitrate is devoid of nitrate tolerance, which has been attributed to the induction of the antioxidant enzyme heme oxygenase (HO)-1. With the present study, we tested whether chronic treatment with pentaerythritol tetranitrate can improve angiotensin II-induced
Monica Lisi et al.
Clinical research in cardiology : official journal of the German Cardiac Society, 101(6), 453-459 (2012-02-03)
Ischemic and pharmacologic preconditioning have great clinical potential, but it remains unclear whether their effects can be maintained over time during repeated exposure.We have previously demonstrated that the acute protective effect of nitroglycerin (GTN) is attenuated during repeated daily administration.
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