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Merck
CN

H-003

Supelco

氢可酮标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C18H21NO3
化学文摘社编号:
125-29-1
分子量:
299.36
UNSPSC代码:
41116107
NACRES:
NA.24

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等级

certified reference material

质量水平

300

表单

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal); Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet

浓度

1.0 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

包装形式

single component solution

储存温度

−20°C

SMILES字符串

N1([C@H]2[C@H]3[C@@]4([C@@H](Oc5c4c(ccc5OC)C2)C(=O)CC3)CC1)C.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O

InChI

1S/C18H21NO3.C4H6O6.H2O/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;5-1(3(7)8)2(6)4(9)10;/h3,6,11-12,17H,4-5,7-9H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10);1H2/t11-,12+,17-,18-;1-,2-;/m01./s1

InChI key

ZICRJLQTAUVSDU-NSJZFRMTSA-N

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相关类别

一般描述

氢可酮是一种半合成的阿片类药物，来源于两种天然存在的阿片类药物可待因或蒂巴因。该药物也称为二氢可待因酮，可用作治疗疼痛的镇痛药和咳嗽或相关疾病的止咳药。该认证加标溶液®适合用作校准品或对照品的起始原料，用于药物研究、止痛药处方监测、临床毒理学和法医分析中的各种GC/MS或LC/MS检测应用。

其他说明

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

监管及禁止进口产品

分析证书(COA)

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How well can urine hydrocodone measurements discriminate between different hydrocodone prescription dosage rates?
Laura J McCloskey et al.
Clinica chimica acta; international journal of clinical chemistry, 419, 119-121 (2013-02-23)
Kathryn P Anastassopoulos et al.
Journal of opioid management, 9(2), 97-109 (2013-05-28)
Pain is a prevalent condition that often involves a neuropathic component. Hydrocodone is one of the most widely used opioids for pain but is often associated with side effects (SEs). This study sought to characterize the experience of patients taking
Elizabeth A Micks et al.
Obstetrics and gynecology, 120(5), 1060-1069 (2012-10-24)
Although hydrocodone-acetaminophen is commonly used for pain control in first-trimester abortion, the efficacy of oral opioids for decreasing pain has not been established. Our objective was to estimate the effect of hydrocodone-acetaminophen on patient pain perception during first-trimester surgical abortion.
FDA panel recommends tighter rules for prescribing opioids.
Michael McCarthy
BMJ (Clinical research ed.), 346, f1012-f1012 (2013-02-16)
Amadeo Pesce et al.
Pain physician, 15(5), E687-E692 (2012-09-22)
A number of studies indicate that 10.8%-34% of patients with chronic pain use illicit drugs. One hypothesis for this occurrence is that some patients may be supplementing their prescription medications with illicit drugs. The primary purpose of this retrospective data
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