H-107
1,25-二羟基维生素 D3-13C3 (25,26,27-13C3)标准液 CRM 溶液
5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®
别名:
氘代化合物1
等级
certified reference material
质量水平
表单
liquid
特点
(Snap-N-Spike®)
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
5 μg/mL in ethanol
mp
-143.99 °C
应用
clinical testing
clinical testing
包装形式
single component solution
储存温度
−70°C
SMILES字符串
O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@]3([H])[C@H](C)CCC[13C](O)([13CH3])[13CH3])([H])[C@]3(C)CCC\2
InChI
1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1/i3+1,4+1,26+1
InChI key
GMRQFYUYWCNGIN-SYUIRNBGSA-N
一般描述
一种稳定标记的内部标准，适用于LC-MS/MS测定1,25-二羟基维生素D3水平。1,25-二羟基维生素D3，也称为骨化三醇，是维生素D的激素活性代谢物，负责调节钙。1,25-二羟基维生素D3的测定用于区分原发性甲状旁腺功能亢进和癌症高钙血症，并用于鉴别维生素D依赖型佝偻病。
其他说明
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Eye Irrit. 2 - Flam. Liq. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
57.2 °F - closed cup
闪点(°C)
14.0 °C - closed cup
法规信息
危险化学品
此项目有
Mark A Crumling et al.
PloS one, 7(12), e53280-e53280 (2013-01-04)
Cyclodextrins are sugar compounds that are increasingly finding medicinal uses due to their ability to complex with hydrophobic molecules. One cyclodextrin in particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is used as a carrier to solubilize lipophilic drugs and is itself being considered as
Eric Wang et al.
Cancer cell, 35(3), 369-384 (2019-02-26)
RNA-binding proteins (RBPs) are essential modulators of transcription and translation frequently dysregulated in cancer. We systematically interrogated RBP dependencies in human cancers using a comprehensive CRISPR/Cas9 domain-focused screen targeting RNA-binding domains of 490 classical RBPs. This uncovered a network of
Fang Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(26), 12986-12995 (2019-06-12)
The aberrant hedgehog (Hh) pathway plays important roles in multiple cancer types, therefore serving as a promising drug target. Current clinically available hedgehog-targeted drugs act mostly by antagonizing the upstream component smoothened; however, both primary and acquired resistance to FDA-approved
Amber J Giles et al.
Journal for immunotherapy of cancer, 6(1), 51-51 (2018-06-13)
Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. However, it is not known if or when corticosteroids can be
Min Seock Jeong et al.
Animal cells and systems, 23(5), 346-354 (2019-11-09)
Niemann-Pick type C disease (NP-C) is a fatal neurodegenerative disorder caused by a deficiency in the function of the NPC1 gene. Malfunction of this gene/protein leads to progressive accumulation of unesterified cholesterol and sphingolipids in many organs, including the brain.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持