H-107
1,25-二羟基维生素 D3-13C3 (25,26,27-13C3)标准液 CRM 溶液
5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®
别名:
氘代化合物1
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
13C3C24H44O3
分子量:
419.61
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-578-6
InChI key
GMRQFYUYWCNGIN-SYUIRNBGSA-N
InChI
1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1/i3+1,4+1,26+1
SMILES string
O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@]3([H])[C@H](C)CCC[13C](O)([13CH3])[13CH3])([H])[C@]3(C)CCC\2
grade
certified reference material
Quality Level
feature
(Snap-N-Spike®)
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
5 μg/mL in ethanol
mp
-143.99 °C
format
single component solution
storage temp.
−70°C
General description
一种稳定标记的内部标准，适用于LC-MS/MS测定1,25-二羟基维生素D3水平。1,25-二羟基维生素D3，也称为骨化三醇，是维生素D的激素活性代谢物，负责调节钙。1,25-二羟基维生素D3的测定用于区分原发性甲状旁腺功能亢进和癌症高钙血症，并用于鉴别维生素D依赖型佝偻病。
Other Notes
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
57.2 °F - closed cup
flash_point_c
14.0 °C - closed cup
法规信息
危险化学品
此项目有
Mark A Crumling et al.
PloS one, 7(12), e53280-e53280 (2013-01-04)
Cyclodextrins are sugar compounds that are increasingly finding medicinal uses due to their ability to complex with hydrophobic molecules. One cyclodextrin in particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is used as a carrier to solubilize lipophilic drugs and is itself being considered as
Fang Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(26), 12986-12995 (2019-06-12)
The aberrant hedgehog (Hh) pathway plays important roles in multiple cancer types, therefore serving as a promising drug target. Current clinically available hedgehog-targeted drugs act mostly by antagonizing the upstream component smoothened; however, both primary and acquired resistance to FDA-approved
Eric Wang et al.
Cancer cell, 35(3), 369-384 (2019-02-26)
RNA-binding proteins (RBPs) are essential modulators of transcription and translation frequently dysregulated in cancer. We systematically interrogated RBP dependencies in human cancers using a comprehensive CRISPR/Cas9 domain-focused screen targeting RNA-binding domains of 490 classical RBPs. This uncovered a network of
Matthew B Pomrenze et al.
Cell reports, 29(1), 13-21 (2019-10-03)
Central amygdala (CeA) neurons that produce corticotropin-releasing factor (CRF) regulate anxiety and fear learning. These CeACRF neurons release GABA and several neuropeptides predicted to play important yet opposing roles in these behaviors. We dissected the relative roles of GABA, CRF
Min Seock Jeong et al.
Animal cells and systems, 23(5), 346-354 (2019-11-09)
Niemann-Pick type C disease (NP-C) is a fatal neurodegenerative disorder caused by a deficiency in the function of the NPC1 gene. Malfunction of this gene/protein leads to progressive accumulation of unesterified cholesterol and sphingolipids in many organs, including the brain.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持