IMPM-005-05
10-Hydroxymorphine solution
100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C17H19NO4
化学文摘社编号:
分子量:
301.34
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6
InChI key
ISVKWTNAIRJURI-AKUCRQHZSA-N
InChI
1S/C17H19NO4/c1-18-7-6-17-9-3-5-11(20)16(17)22-15-10(19)4-2-8(12(15)17)14(21)13(9)18/h2-5,9,11,13-14,16,19-21H,6-7H2,1H3/t9-,11-,13-,14?,16-,17-/m0/s1
SMILES string
CN1CC[C@]23[C@H]4Oc5c(O)ccc(C(O)[C@@H]1[C@@H]2C=C[C@@H]4O)c35
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in methanol
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
storage temp.
−20°C
Quality Level
General description
10-Hydroxymorphine is a potential impurity from the production of morphine pharmaceutical formulations. Morphine is a potent opiate analgesic drug used to relieve both acute and chronic severe pain. This Certified Snap-N-Spike® Solution is applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as impurity identification.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
Morphine impurity with opioid activity is identified as 10 alpha-hydroxymorphine.
H Farsam et al.
Pharmaceutical research, 7(11), 1205-1207 (1990-11-01)
Seán S Kelly et al.
Journal of pharmaceutical sciences, 92(3), 485-493 (2003-02-15)
Stability testing of morphine sulfate formulated with nonpareil sugar seeds (consisting of sucrose and starch) and fumaric acid revealed the formation of the three impurities 5-(hydroxymethyl)-2-furfural, 10-hydroxymorphine and 10-oxomorphine. 5-(Hydroxymethyl)-2-furfural was isolated via semipreparative HPLC utilizing volatile mobile phase constituents
B Proksa
Journal of pharmaceutical and biomedical analysis, 20(1-2), 179-183 (2000-03-07)
Separation of morphine and its oxidation products (10-S-hydroxymorphine, pseudomorphine and morphine N-oxide) by capillary zone electrophoresis in Tris-borate buffer in the presence of cyclodextrins was studied. Pyridoxine was used as an internal standard.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持