Merck
CN
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文件

安全信息

L-025

Supelco

(−)-Levamisole hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C11H12N2S
CAS号:
16595-80-5
分子量:
204.29
MDL编号:
MFCD00792481
PubChem化学物质编号:
329817345
NACRES:
NA.24

等级

certified reference material

质量水平

300

形式

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

1.0 mg/mL in methanol (as free base)

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

pharmaceutical (small molecule)

格式

single component solution

储存温度

−20°C

SMILES字符串

C1CN2C[C@@H](N=C2S1)c3ccccc3

InChI

1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1

InChI key

HLFSDGLLUJUHTE-SNVBAGLBSA-N

相关类别

一般描述

Levamisole, an antihelminthic drug used to treat worm infestations in humans and animals, is an adulterant and cutting agent found in cocaine sold in the US and Canada. From 2008-2009, levamisole was detected in 69% of cocaine samples seized by the US Drug Enforcement Administration (DEA).

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

危险化学品

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Bashir A Lone et al.
Tropical animal health and production, 45(3), 743-749 (2012-10-16)
The aim of this study was to evaluate the anthelmintic and antimicrobial efficacy of Euphorbia helioscopia crude extracts. A worm motility inhibition assay and egg hatch assay were used for in vitro study, and a faecal egg count reduction assay
Anders N Hansen et al.
PloS one, 7(9), e45405-e45405 (2012-10-02)
Inhibition of angiogenesis is a promising addition to current cancer treatment strategies. Neutralization of vascular endothelial growth factor by monoclonal antibodies is clinically effective but may cause side effects due to thrombosis. Low molecular weight angiogenesis inhibitors are currently less
Lauren Strazzula et al.
Journal of the American Academy of Dermatology, 69(6), 954-959 (2013-10-01)
Levamisole is present as a contaminant or additive in most cocaine sold in the United States. Cases of agranulocytosis attributed to levamisole-tainted cocaine have been widely described. A vasculopathic reaction to levamisole has also been reported; however, diagnostic features such as
Jonathan Graf
Current opinion in rheumatology, 25(1), 50-55 (2012-12-01)
Cocaine use is associated with several rheumatic syndromes. This review summarizes these clinical manifestations and highlights recent developments linked to levamisole-adulterated cocaine. Cocaine use has been linked to several distinctive syndromes that can be difficult to distinguish from idiopathic rheumatic
Barbara Deracinois et al.
PloS one, 7(10), e48428-e48428 (2012-11-03)
Although the physiological properties of the blood-brain barrier (BBB) are relatively well known, the phenotype of the component brain capillary endothelial cells (BCECs) has yet to be described in detail. Likewise, the molecular mechanisms that govern the establishment and maintenance
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