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Merck
CN

M-123

酒石酸美托洛尔标准液 酒石酸酯 溶液

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式（希尔记法）:
C15H25NO3 · 0.5 C4H6O6
化学文摘社编号:
56392-17-7
分子量:
342.41
NACRES:
NA.24
PubChem Substance ID:
329817863
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD23141017

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产品名称

酒石酸美托洛尔标准液 酒石酸酯 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

InChI key

YGULWPYYGQCFMP-UHFFFAOYSA-N

InChI

1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)

SMILES string

CC(C)NCC(COC1=CC=C(CCOC)C=C1)O.CC(C)NCC(COC2=CC=C(CCOC)C=C2)O.OC(C(O)=O)C(C(O)=O)O

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

Quality Level

300

Gene Information

human ... ADRB1(153)

相关类别

General description

经认证的溶液标准品，适用于通过LC-MS/MS或GC/MS进行临床毒理学或法医分析。美托洛尔用于多种心脏病的治疗，包括高血压，心绞痛和心动过速。这种β受体阻滞剂以Lepressor和Toprol XL®的商品名出售。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Toprol XL is a registered trademark of Astrazeneca AB

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

危险化学品
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Thomas Kahan et al.
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Although stable angina pectoris often carries a favourable prognosis, it remains important to identify patients with an increased risk of cardiovascular (CV) complications. Many new markers of disease activity and prognosis have been described. We evaluated whether common and easily
Iu M Alekseeva et al.
Kardiologiia, 52(11), 86-91 (2012-12-15)
We present analysis of a case history of a patient with rare congenital heart disorder - Bland-White-Garland syndrome. The 25 years old women was first diagnosed with this disorder during an examination in the cardiological department of the Moscow clinical
A L Vertkin et al.
Klinicheskaia meditsina, 91(3), 31-35 (2013-06-26)
Patients with acute coronary syndrome and elevated ST segment in the pre-hospital phase were treated with metoprolol succinate (MS) and thrombolytic therapy. Severe and moderate pain decreased by 54.1 and 16.1% respectively within 60 min after MS intake. Systolic (SAP)
Abdulhakim A A Khaled et al.
Acta poloniae pharmaceutica, 70(4), 743-747 (2013-08-08)
This study was aimed to develop level A, B and C in vitro-in vivo correlation (IVIVC) for encapsulated metoprolol tartrate (T1, T2 and T3 having metoprolol tartrate/polymer ratio of 1: 1, 1: 1.5 and 1: 2,w/w). The in vitro data
B Sasko et al.
Deutsche medizinische Wochenschrift (1946), 137(50), 2637-2640 (2012-12-12)
A 70-year-old woman was admitted to hospital with progressive chest pain. Coronary angiography demonstrated a significant stenosis of the left descending artery (LAD), which was treated by percutaneous coronary intervention (PCI) and stent implantation. During this intervention, a coronary perforation
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