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Merck
CN

M-153

甲氨蝶呤-D3标准液 CRM 溶液

100 μg/mL in methanol with 0.01N NaOH, ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式(希尔记法):
C20H19N8O5D3
化学文摘社编号:
分子量:
457.46
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6
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产品名称

甲氨蝶呤-D3标准液 CRM 溶液, 100 μg/mL in methanol with 0.01N NaOH, ampule of 1 mL, certified reference material, Cerilliant®

InChI key

FBOZXECLQNJBKD-FIBGUPNXSA-N

InChI

1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/i1D3

SMILES string

[2H]C([2H])([2H])N(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol with 0.01N NaOH

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

Quality Level

General description

一个适用于通过 LC-MS/MS 对甲氨蝶呤患者血清样品进行治疗性药物监测分析的内标。甲氨蝶呤用于治疗癌症和自身免疫性疾病,是一种抗代谢物和抗叶酸药物,由临床实验室进行监控,以确保患者服用量维持在该药物的治疗范围内。Snap-N-Spike® 解决方案格式可让实验室不需要对氨甲蝶呤等有害物质进行称重操作,显着降低处理剧毒粉末相关的职业暴露危害,并提供在使用前立即掺入所选基质的功能。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Met. Corr. 1 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

危险化学品
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An effective wipe sampling and LC-MS/MS method was developed to simultaneously analyze six commonly administered antineoplastic drugs in stainless steel surface. The analyzed drugs were methotrexate, paclitaxel, cyclophosphamide, 5-fluorouracil, vincristine, and oxaliplatin, a frequently prepared antineoplastic drug that has not

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