M-920
Maprotiline hydrochloride solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
等级
certified reference material
质量水平
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol (as free base)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
包装形式
single component solution
储存温度
2-8°C
SMILES字符串
Cl.CNCCCC12CCC(c3ccccc13)c4ccccc24
InChI
1S/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H
InChI key
NZDMFGKECODQRY-UHFFFAOYSA-N
基因信息
human ... SLC6A2(6530)
一般描述
Maprotiline is a tetracyclic antidepressant marketed under the trade name Ludiomil for treatment of depression. This Certified Spiking Solution® suitable for use in urine drug testing, clinical toxicology, or forensic analysis by LC-MS/MS or GC/MS.
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
49.5 °F - closed cup
闪点(°C)
9.7 °C - closed cup
法规信息
危险化学品
此项目有
Suzanne M Cloonan et al.
Leukemia & lymphoma, 51(3), 523-539 (2010-02-10)
The discovery that some selective serotonin transporter- (SSRI) and norepinephrine transporter- (NSRI) targeting antidepressants have the potential to act as anticancer agents adds greatly to their diverse pharmacological application. We report that the SSRI fluoxetine and the NSRI maprotiline are
Edward C Lauterbach et al.
The Journal of neuropsychiatry and clinical neurosciences, 22(1), 8-18 (2010-02-18)
This manuscript reviews the preclinical in vitro, ex vivo, and nonhuman in vivo effects of psychopharmacological agents in clinical use on cell physiology with a view toward identifying agents with neuroprotective properties in neurodegenerative disease. These agents are routinely used
V Hajhashemi et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 59(12), 1053-1059 (2010-06-25)
To explore the site of action of maprotiline, as an atypical antidepressant, on carrageenan-induced paw edema. Male Wistar rats were used. Firstly, the anti-inflammatory effect of systemic maprotiline (12.5, 25 and 50 mg kg(-1)) was assessed using a paw edema
Su-Hyun Jo et al.
Archives of pharmacal research, 30(4), 453-460 (2007-05-11)
Maprotiline, an atypical antidepressant, can induce prolonged QT and torsades de pointes. We studied the effects of maprotiline on human ether-a-go-go-related gene (HERG) channels expressed in Xenopus oocytes and HEK293 cells. Maprotiline induced a concentration-dependent decrease in current amplitudes at
J E Warnick et al.
Journal of psychopharmacology (Oxford, England), 23(2), 143-156 (2008-06-03)
The clinical syndromes of anxiety and depression are now thought to exist along a temporal continuum and this construct has been modelled in a preclinical setting in chicks separated from conspecifics. This research sought to further the validity of the
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