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经验公式(希尔记法):
C14H14O3
化学文摘社编号:
分子量:
230.26
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
InChI key
CMWTZPSULFXXJA-VIFPVBQESA-N
InChI
1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
SMILES string
COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
2-8°C
Quality Level
Gene Information
human ... PTGS1(5742), PTGS2(5743)
General description
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) sold under the trade name Aleve®. This COX inhibitor is indicated for the treatment of pain, fever, inflammation and stiffness. This Certified Spiking Solution® is applicable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or pharmaceutical research.
Legal Information
Aleve is a registered trademark of Bayer Healthcare LLC
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
危险化学品
此项目有
Raffaele Marotta et al.
Water research, 47(1), 373-383 (2012-11-06)
The kinetics of photodegradation of the non steroidal anti-inflammatory drug naproxen (+)-S-2-(6-methoxynaphthalen-2-yl)propanoic acid, an emerging organic pollutant, was studied in aqueous solutions under deaerated and aerated conditions. The photolysis experiments were carried out under monochromatic irradiation (λ = 254 nm)
Pain relievers: bad for your heart? People with heart disease should avoid prolonged use of certain anti-inflammatory drugs, Naproxen (Aleve) is safest.
Harvard men's health watch, 17(6), 3-3 (2013-07-04)
Christopher Lockhart et al.
Biophysical journal, 103(11), 2341-2351 (2013-01-04)
All-atom explicit solvent model and replica exchange molecular dynamics were used to investigate binding of Alzheimer's biomarker FDDNP to the Aβ(10-40) monomer. At low and high concentrations, FDDNP binds with high affinity to two sites in the Aβ(10-40) monomer located
Diana Marcela Aragón et al.
Journal of microencapsulation, 30(3), 218-224 (2013-02-02)
Naproxen (NPX)-loaded poly-(D,L-lactic-co-glycolic acid) (PLGA) microparticles were prepared by the emulsion-solvent evaporation method. The different organic solvents used significantly affects the properties of the microparticles obtained. These microparticles exhibited a controlled release profile that extends up to 15 days depending
Gounathan Adly et al.
The Annals of pharmacotherapy, 47(2), e8-e8 (2013-02-07)
To describe a case of continued aspirin use for primary prevention of a cardiovascular event in a patient post-aspirin-induced upper gastrointestinal (GI) bleed and evaluate published evidence to determine whether reinitiating aspirin therapy for this patient was appropriate. A 65-year-old
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