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Merck
CN

N-071

(±)-降烟碱 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式(希尔记法):
C9H12N2
化学文摘社编号:
分子量:
148.20
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6
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grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

C1CNC(C1)c2cccnc2

InChI

1S/C9H12N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7,9,11H,2,4,6H2

InChI key

MYKUKUCHPMASKF-UHFFFAOYSA-N

General description

Nornicotine is a tobacco alkaloid and nicotine metabolite. Since virtually all tobacco products contain nornicotine, smoking or chewing tobacco exposes the user to this nicotine alkaloid. In urine testing by GC/MS or LC/MS, nornicotine is used as an indicator of smoking or use of chewing tobacco or nicotine replacement products.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

危险化学品

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Joseph R Holtman et al.
Pharmacology, biochemistry, and behavior, 94(3), 352-362 (2009-10-06)
Neuronal nicotinic acetylcholinic receptors (nAChR) are promising targets for the development of novel analgesics. Nicotine and other nAChR-agonists produce profound analgesia in rodent models of acute and persistent pain. However, significant side-effects are of concern. Nornicotine (N-desmethyl-nicotine) appears to activate
François Marclay et al.
Forensic science international, 213(1-3), 73-84 (2011-07-02)
Tobacco consumption is a global epidemic responsible for a vast burden of disease. With pharmacological properties sought-after by consumers and responsible for addiction issues, nicotine is the main reason of this phenomenon. Accordingly, smokeless tobacco products are of growing popularity
Wojciech Piekoszewski et al.
Przeglad lekarski, 66(10), 593-597 (2009-01-01)
The assay of biomarkers in biological material is the most popular and reliable method in estimate exposure to tobacco smoke. Nicotine and its metabolites qualify to the most specific biomarkers for tobacco smoke. Currently the most often used are cotinine



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货号GTIN
N-071-1ML04061834081845