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Merck
CN

O-002

羟考酮标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C18H21NO4
化学文摘社编号:
76-42-6
分子量:
315.36
NACRES:
NA.24
PubChem Substance ID:
329818811
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00190613

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InChI key

BRUQQQPBMZOVGD-XFKAJCMBSA-N

InChI

1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1

SMILES string

COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal), kontrollierte Droge in Deutschland

Quality Level

300

Gene Information

human ... OPRM1(4988)

storage temp.

−20°C

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

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General description

该认证的加标溶液®适用于从临床毒理学和尿液药物测试到法医分析的羟考酮GC/MS或LC/MS测试的许多应用。羟考酮是一种半合成阿片类镇痛药，以许多商品名出售，包括OxyContin®和Percocet®，用于治疗中度至重度疼痛。羟考酮还以“Roxies”，“Blues”和“Perks”等街头名称非法出售。

Other Notes

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
OxyContin is a registered trademark of Purdue Pharma L.P.
Percocet is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

监管及禁止进口产品
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Myoung Kim et al.
Journal of opioid management, 9(3), 189-204 (2013-06-19)
This article describes the rationale and design of the Oxycodone Users Registry (OUR) study and lessons learned during study development and data collection. The OUR study used a prospective registry design. Sixty-five academic and private medical practices across the United
Sanjay Merchant et al.
Journal of opioid management, 9(1), 51-61 (2013-05-28)
To evaluate a composite measure for chronic pain that balances pain relief with tolerability. Post hoc meta-analysis of three randomized, multicenter, double-blind studies. Subjects with moderate-to-severe chronic osteoarthritis knee pain or low back pain who had been randomized to receive
FDA ban of generic oxycodone calls into question Health Canada's approval.
Adam Miller
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 185(9), E381-E382 (2013-05-01)
Kenneth Kirsh et al.
Journal of pain & palliative care pharmacotherapy, 26(4), 348-361 (2013-05-16)
Prescription opioids are prescribed increasingly for the management of chronic pain, and this has been accompanied by a dramatic rise in opioid-related abuse, addiction, and overdose deaths. Reports of abuse involving nonoral administration (e.g., snorting, injecting) of prescription opioids are
Prescrire international, 22(134), 10-11 (2013-02-02)
At high doses of oxycodone, the fixed-dose combination of oxycodone plus naloxone complicates therapeutic management and will likely have lower analgesic efficacy.
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