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P-073

喷他佐辛溶液

Name: 喷他佐辛 溶液
Brand: CERILLIAN

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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关于此项目

经验公式（希尔记法）:

C₁₉H₂₇NO

化学文摘社编号:

359-83-1

分子量:

285.42

NACRES:

NA.24

UNSPSC Code:

41116107

EC Number:

200-659-6

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grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

O=C(C1=C2C(NC(CCOCCC(O)=O)=O)=CC=C1)N([C@H]3CCC(NC3=O)=O)C2=O.O=C(C4=C5C(NC(CCOCCC(O)=O)=O)=CC=C4)N([C@H]6CCC(NC6=O)=O)C5=O

InChI

1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3

InChI key

VOKSWYLNZZRQPF-UHFFFAOYSA-N

Gene Information

human ... SIGMAR1(10280)

General description

A Certified Spiking Solution^® applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as pain prescription monitoring, urine drug testing, forensic analysis, clinical toxicology, or pharmaceutical research. Pentazocine is a synthetic opioid analgesic used for treatment of moderate to severe pain. This painkiller is formulated in combination with naloxone or as a single agent under the trade names Talwin^® and Talwin^® NX, respectively.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Talwin is a registered trademark of Hospira, Inc.

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

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Characterization of ligand binding to the σ(1) receptor in a human tumor cell line (RPMI 8226) and establishment of a competitive receptor binding assay.

Stefanie Brune et al.

Assay and drug development technologies, 10(4), 365-374 (2011-12-24)

The standard assay for the determination of σ(1) receptor affinities of novel compounds is a competitive binding assay using [(3)H]-(+)-pentazocine as radioligand and membrane preparations from guinea pig brain. Herein, a novel competitive binding assay was developed employing the hematopoietic

Sulfation of buprenorphine, pentazocine, and naloxone by human cytosolic sulfotransferases.

Katsuhisa Kurogi et al.

Drug metabolism letters, 6(2), 109-115 (2012-09-06)

Buprenorphine, pentazocine, and naloxone are opioid drugs used for the treatment of pain and opioid dependence or overdose. Sulfation as catalyzed by the cytosolic sulfotransferases (SULTs) is involved in the metabolism of a variety of xenobiotics including drug compounds. Sulfation

(+)-Morphine attenuates the (-)-morphine-produced tail-flick inhibition via the sigma-1 receptor in the mouse spinal cord.

Leon F Tseng et al.

Life sciences, 89(23-24), 875-877 (2011-10-13)

We have previously demonstrated that pretreatment with (+)-morphine given intrathecally attenuates the intrathecal (-)-morphine-produced tail-flick inhibition. The phenomenon has been defined as antianalgesia against (-)-morphine-produced analgesia. Present experiments were then undertaken to determine if the antianalgesic effect induced by (+)-morphine

Administration of additional analgesics can decrease the incidence of paradoxical reactions in patients under benzodiazepine-induced sedation during endoscopic transpapillary procedures: prospective randomized controlled trial.

Torahiko Terui et al.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 25(1), 53-59 (2013-01-05)

The aim of the present study was to evaluate the efficacy and safety of giving pentazocine as an analgesic with benzodiazepine during endoscopic retrograde cholangiopancreatography (ERCP). The paradoxical reactions (PR) incidence was evaluated as an indicator of usefulness. Transcutaneous arterial

[Effect of pentazocine on the bispectral index during nitrous oxide-sevoflurane anesthesia].

Hiroshi Oyake et al.

Masui. The Japanese journal of anesthesiology, 60(10), 1128-1134 (2011-11-25)

The effect of pentazocine on the bispectral index (BIS) has not been reported. In this study, we have examined whether pentazocine alters the bispectral index during nitrous oxide-sevoflurane anesthesia. Thirty surgical patients were enrolled in this double-blind, randomized study. Anesthesia

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全球贸易项目编号

货号	GTIN
P-073-1ML	04061834253860

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