Merck
CN
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文件

安全信息

P-916

Supelco

Paroxetine maleate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C19H20FNO3 · C4H4O4
CAS号:
64006-44-6
分子量:
445.44
EC 号:
200-659-6
NACRES:
NA.24

等级

certified reference material

质量水平

300

形式

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

manufacturer/tradename

Cerilliant®

浓度

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

格式

single component solution

储存温度

−20°C

SMILES string

OC(=O)\C=C/C(O)=O.Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3

InChI

1S/C19H20FNO3.C4H4O4/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;5-3(6)1-2-4(7)8/h1-6,9,14,17,21H,7-8,10-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,17-;/m0./s1

InChI key

AEIUZSKXSWGSRU-QXGDPHCHSA-N

Gene Information

human ... SLC6A4(6532)

相关类别

一般描述

Paroxetine, marketed under trade names such as Paxil® or Aropax, is an SSRI antidepressant used to treat many conditions in adults from major depression and obsessive-compulsive disorder to several anxiety disorders. Suitable uses for this certified solution standard include as a starting material for calibrators and controls in LC/MS or GC/MS paroxetine testing applications such as urine drug testing, prescription monitoring, clinical toxicology, or forensic analysis.

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Paxil is a registered trademark of GlaxoSmithKline LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

危险化学品

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Wojciech Waldman et al.
Przeglad lekarski, 69(8), 587-588 (2012-12-19)
Hydroxycarbamide (HCB), also known as hydroxyurea, is an urea derivative used mainly as antineoplastic and antisickling agent. We described a 31 yrs. female, with essential thrombocythemia, who was admitted to our clinic because of double suicidal ingestion of hydroxycarbamide. First
Zheng-Wu Peng et al.
Molecular and cellular biochemistry, 375(1-2), 105-113 (2013-01-08)
Paroxetine is a widely used antidepressant in clinic. Besides its role in inhibition of serotonin reuptake, resent studies indicate that the increase of hippocampal neurogenesis is also involved in its pharmacology. However, only limited data are available in this regard
Wei-Rong Lin et al.
Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 32(12), 1063-1069 (2013-01-11)
To compare the differences in the efficacy on agitated depression among the alliance therapy of acupuncture and seroxat, the alliance therapy of electroacupuncture and seroxat and the simple application of seroxat. One hundred and two cases were randomized into a
GSK paid smaller companies to delay generic versions of paroxetine, says fair trade body.
Clare Dyer
BMJ (Clinical research ed.), 346, f2566-f2566 (2013-04-24)
Arun V Ravindran et al.
Asian journal of psychiatry, 6(2), 157-161 (2013-03-08)
Few published studies have evaluated selective serotonin reuptake inhibitors in dysthymia without current co-morbid major depression. In this 12-week study, 40 dysthymic patients were randomly assigned to either placebo (n=19) or 20-40 mg/day of paroxetine (n=21). At endpoint, the paroxetine
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