biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
BED5 57-6, monoclonal
species reactivity
mouse, rat, hamster, monkey, human
packaging
antibody small pack of 25 μg
manufacturer/tradename
Upstate®
technique(s)
immunofluorescence: suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Gene Information
human ... TERF1(7013)
General description
~60 kDa
Immunogen
人 TRF1 蛋白
Application
该抗 TRF1 抗体克隆 BED5 57-6 经过验证可用在 WB、IF 中检测 TRF1。
Biochem/physiol Actions
检测 TRF1
Physical form
含 0.05% NaN3 的 PBS 中的亲和的纯化免疫球蛋白
形式:纯化的
Analysis Note
通过蛋白质印迹在 Hela 细胞裂解液中进行了常规评估。
Other Notes
浓度:请参考批次特异性浓缩物的分析证书。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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相关内容
"Recognizing both the tremendous opportunities and the challenges facing cancer research, we are dedicated to developing and refining tools and technologies for the study of cancer. With our comprehensive portfolio, including the Upstate®, Chemicon®, and Calbiochem® brands of reagents and antibodies, researchers can count on dependable, high quality solutions for analyzing all the hallmarks of cancer."
PTOP and TRF1 help enhance the radio resistance in breast cancer cell.
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Emily Mason-Osann et al.
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Cancer cells can activate the alternative lengthening of telomeres (ALT) pathway to promote replicative immortality. The ALT pathway promotes telomere elongation through a homologous recombination pathway known as break-induced replication (BIR), which is often engaged to repair single-ended double-stranded breaks
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