05-1066
抗胰岛素抗体，克隆E11D7
clone E11D7, from mouse
别名:
Anti-IDDM, Anti-IDDM1, Anti-IDDM2, Anti-ILPR, Anti-IRDN, Anti-MODY10, Anti-PNDM4
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
E11D7, monoclonal
Application:
ELISA
immunohistochemistry
immunohistochemistry
Species reactivity:
human
Citations:
6
Technique(s):
ELISA: suitable
immunohistochemistry: suitable (paraffin)
immunohistochemistry: suitable (paraffin)
Uniprot accession no.:
产品名称
抗胰岛素抗体，克隆E11D7, clone E11D7, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
E11D7, monoclonal
species reactivity
human
species reactivity (predicted by homology)
rat, mouse
packaging
antibody small pack of 25 μg
technique(s)
ELISA: suitable
immunohistochemistry: suitable (paraffin)
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Quality Level
Gene Information
human ... INS(3630)
mouse ... Ins1(16333)
rat ... Ins1(24505)
Analysis Note
免疫组化分析：
20 μg/mL 的该抗体在 β 细胞中检测到胰岛素。
20 μg/mL 的该抗体在 β 细胞中检测到胰岛素。
Application
ELISA（直接）分析：将胰岛素包被的平板与抗胰岛素一起孵育，将克隆的 E11D7 使用 PBST 通过 2 倍连续稀释，从 5 g/mL 稀释至 0.01 g/mL。
抗胰岛素抗体，克隆 E11D7 可检测胰岛素水平，&经发布 & 验证可用于 ELISA、IH（P）。
研究子类别
胰岛素/能量信号传导
葡萄糖/糖原代谢
代谢激素 & 受体
胰岛素/能量信号传导
葡萄糖/糖原代谢
代谢激素 & 受体
研究类别
信号
代谢
信号
代谢
Biochem/physiol Actions
识别胰岛素
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
6kda
胰岛素是调节碳水化合物代谢的多肽激素。除了作为碳水化合物稳态的主要因子外，它还对脂肪代谢有影响。
Immunogen
人重组胰岛素
表位：胰岛素
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
在 0.1M Tris-甘氨酸（pH7.4），150mM NaCl 和 0.05％NaN3 中的纯化的小鼠单克隆 IgG1κ
形式：纯化的
蛋白 G 纯化
Preparation Note
自收到之日起，在 2-8ºC 条下可稳定保存 1 年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Activation of PPAR? up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate.
Mingming Cao,Yang Long,Yuzhen Tong,Jun Wan,Nanwei Tong
Molecular and Cellular Biochemistry null
Yoshimitsu Taguchi et al.
The Journal of biological chemistry, 291(23), 12029-12038 (2016-04-10)
Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite that regulates basic cell functions through metabolic and signaling pathways. Intracellular metabolism of S1P is controlled, in part, by two homologous S1P phosphatases (SPPases), 1 and 2, which are encoded by the Sgpp1 and
Mi Ran Choi et al.
Journal of ginseng research, 41(4), 503-512 (2017-10-13)
Chronic heavy alcohol consumption may raise the risk of developing type 2 diabetes mellitus. Saponins inhibit apoptosis of pancreatic islet cells and reduce lipid parameters. The present study was designed to investigate the effect of saponin on chronic ethanol-treated diabetic
Gabriel Cao et al.
PloS one, 16(6), e0243340-e0243340 (2021-06-12)
The objective of this work was to analyze the structural changes of the pancreatic islets in rats, after 6 month consuming regular and light cola for 6 months. Also, we have analyzed the possible role of PDX-1 in that process.
Rehab F Abdel-Rahman et al.
Journal of nutritional science, 9, e2-e2 (2020-02-12)
Ficus deltoidea var. deltoidea Jack (FD) is a well-known plant used in Malay folklore medicine to lower blood glucose in diabetic patients. For further research of the antihyperglycemic mechanisms, the protein tyrosine phosphatase 1B (PTP1B)-inhibitory effect of FD was analysed
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