05-175
抗-Myb抗体，克隆1-1
clone 1-1, Upstate®, from mouse
别名:
Avian myeloblastosis viral (v-myb) oncogene homolog 2 c-myb protein (140 AA), v-myb avian myeloblastosis viral oncogene homolog, v-myb avian myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral on
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
1-1, monoclonal
Application:
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Species reactivity:
mouse, human
Citations:
78
Technique(s):
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗-Myb抗体，克隆1-1, clone 1-1, Upstate®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1-1, monoclonal
species reactivity
mouse, human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MYB(4602)
Analysis Note
对来自RIPA细胞的RIPA裂解液进行了常规评估。
蛋白质印迹分析：
0.5-2 μg/mL该批次产品在Jurkat细胞的20 μg IPA裂解液中检测到Myb。
蛋白质印迹分析：
0.5-2 μg/mL该批次产品在Jurkat细胞的20 μg IPA裂解液中检测到Myb。
对照
阳性抗原对照：目录# 12-303，Jurkat细胞裂解液。
阳性抗原对照：目录# 12-303，Jurkat细胞裂解液。
Application
免疫沉淀
4 μg先前批次产品已在Jurkat细胞裂解液中对Myb进行了免疫沉淀。
免疫细胞化学：
4 μg先前批次产品已在Jurkat细胞裂解液中对Myb进行了免疫沉淀。
免疫细胞化学：
抗Myb抗体，克隆1-1是用于检测Myb（也称为禽成纤维细胞病病毒（v-myb）癌基因同源物2 c-myb蛋白（140 Aa））的小鼠单克隆抗体，& 已在IHC，IP & WB中进行了验证。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
该抗体可识别Myb，Mr 80 kDa，含有401-636的C端氨基酸（Salomoni，P.，1997）。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
80 kDa
Myb是转录激活因子。它是一种DNA结合蛋白，可特异性识别序列5′-YAAC[GT]G-3′。Myb在控制造血祖细胞的增殖和分化中起重要作用。
Immunogen
通过SDS-PAGE（Nicot，C.，2001）克隆1-1纯化的重组鼠Myb。
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
形式：纯化
硫酸铵沉淀，凝胶过滤和和李子交换层析
纯化的小鼠单克隆IgG2aκ，溶于含有0.1 M Tris-甘氨酸（pH 7.4），0.15 mM NaCl和0.05％叠氮化钠的缓冲液中。冷冻溶液。
Preparation Note
自收到之日起在-20°C可稳定保存1年。 避免反复冻融。 为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Zhenglong Wu et al.
Journal of experimental & clinical cancer research : CR, 32, 98-98 (2013-12-03)
Mir-29 microRNA families are involved in regulation of various types of cancers. Although Mir-29 was shown to play an inhibitory role in tumorigenesis, the role of Mir-29 in breast cancer still remains obscure. In this study, we showed that Mir-29a
Delivery of c-myb antisense oligodeoxynucleotides to human neuroblastoma cells via disialoganglioside GD(2)-targeted immunoliposomes: antitumor effects.
G Pagnan, D D Stuart, F Pastorino, L Raffaghello, P G Montaldo, T M Allen, B Calabretta, M Ponzoni
Journal of the National Cancer Institute null
XinJing Tang et al.
Nucleic acids research, 36(2), 559-569 (2007-12-07)
Light-activated antisense oligodeoxynucleotides (asODNs) were developed to control the degradation of target mRNA in living cells by RNase H. A 20-mer asODN previously shown to target c-myb, a hematopoietic transcription factor, was covalently attached via a photocleavable linker (PL) to
c-Maf interacts with c-Myb to down-regulate Bcl-2 expression and increase apoptosis in peripheral CD4 cells.
Siying Peng,Saif Lalani,Jianmei W Leavenworth,I-Cheng Ho,Mary E Pauza
European Journal of Immunology null
cDNA array analysis of alterations in gene expression in the promyelocytic leukemia cell line, HL-60, after apoptosis induction with etoposide.
M Bj?rling-Poulsen, O-G Issinger
Apoptosis null
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