05-235
EF1α抗体，克隆CBP-KK1
clone CBP-KK1, Upstate®, from mouse
别名:
CTCL tumor antigen, EF1a-like protein, Elongation factor 1 A-1, Elongation factor Tu, Leukocyte receptor cluster member 7, cervical cancer suppressor 3, elongation factor 1 alpha subunit, elongation factor 1-alpha, eukaryotic translation elongation facto
产品名称
EF1α抗体，克隆CBP-KK1, clone CBP-KK1, Upstate®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
CBP-KK1, monoclonal
species reactivity
bacteria, Saccharomyces cerevisiae
species reactivity (predicted by homology)
mammals
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... EEF1A1(1915)
Analysis Note
蛋白质印迹分析：
0.5-2 µg/mL的该批次在未刺激的A431细胞RIPA裂解液中检测到EF1α。先前批次在人Jurkat和小鼠3T3/A31 RIPA细胞裂解液中检测到EF1α。
阳性抗原对照：货号12-301，未刺激的A431细胞裂解液。加入2.5µL 2-巯基乙醇/100µL裂解液，煮沸5分钟以减少制备量。在微凝胶每个泳道上样20µg经还原的裂解液。
Application
4 µg先前批次可免疫沉淀A431 RIPA细胞裂解液中的EF1α。
RNA 代谢&结合蛋白
RNA结合蛋白（RBP）
蛋白运输
Biochem/physiol Actions
Disclaimer
General description
在66%的Felty综合征患者中，α1同工型被确定为自身抗原。研究发现，α1同工型的基因在许多染色体上有多个拷贝，其中一些（如果不是全部）代表不同的假基因。α2的基因可能在卵巢癌的进展中起关键作用。
Immunogen
Other Notes
Physical form
Preparation Note
处理建议：
收到后，在取下瓶盖之前，将小瓶离心并轻轻混合溶液。分装到微量离心管中，并储存于-20ºC。避免反复冻融循环，以免损坏IgG和影响产品性能。
Legal Information
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
相关内容
All eukaryotic organisms require tight regulation of gene expression for complex processes such as development, differentiation, cell specification, and responses to environmental stimuli. Many genes are regulated post-transcriptionally, in addition to transcriptional mechanisms of gene regulation. RNA-binding proteins (RBPs) are essential for post-transcriptional gene regulation, linking transcription and translation in many processes including transcription, splicing, export, rate of translation and turnover. In all of these events, RBPs coordinate regulation of the amount of protein produced from mRNA transcripts.
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