05-246
抗整合素α 1抗体（克隆5E8D9）
clone 5E8D9, Upstate®, from mouse
别名:
Anti-CD49a, Anti-VLA1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
5E8D9, monoclonal
Application:
ICC, Neutral
Citations:
21
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5E8D9, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, neutralization: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGA1(3672)
General description
150kDa
Immunogen
纯化的人整合素α1
Application
抗整合素α1抗体（克隆5E8D9）是一种针对整合素α1的抗体，可用于IC和NEUT。
研究子类别
整合素
整合素
研究类别
细胞结构
细胞结构
Biochem/physiol Actions
整合素α1
Physical form
0.1M Tris-甘氨酸，pH 7.4，0.15M NaCl
形式：纯化
蛋白A层析
Preparation Note
在-20°C下可保存2年
Analysis Note
通过免疫细胞化学对冷乙醇固定细胞进行常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Functional regulation of the human integrin VLA-1 (CD49a/CD29) by divalent cations and stimulatory beta 1 antibodies.
Luque, A, et al.
Febs Letters, 346, 278-284 (1994)
Regulation of the VLA integrin-ligand interactions through the beta 1 subunit.
Arroyo, A G, et al.
The Journal of cell biology, 117, 659-670 (1992)
S Makihira et al.
The Journal of biological chemistry, 274(16), 11417-11423 (1999-04-10)
Cartilage matrix protein (CMP; also known as matrilin-1), one of the major noncollagenous proteins in most cartilages, binds to aggrecan and type II collagen. We examined the effect of CMP on the adhesion of chondrocytes and fibroblasts using CMP-coated dishes.
Pro-adhesive and chemotactic activities of thrombospondin-1 for breast carcinoma cells are mediated by alpha3beta1 integrin and regulated by insulin-like growth factor-1 and CD98.
S Chandrasekaran, N H Guo, R G Rodrigues, J Kaiser, D D Roberts
The Journal of Biological Chemistry null
D A Calderwood et al.
The Journal of biological chemistry, 272(19), 12311-12317 (1997-05-09)
The integrin alpha1beta1 is a cell surface receptor for collagens and laminin. The alpha1 subunit contains an A-domain, and the A-domains of other integrins are known to mediate ligand binding. To determine the role of the alpha1 A-domain in ligand
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