05-363
抗细胞周期蛋白E抗体，克隆HE12
clone HE12, Upstate®, from mouse
别名:
Anti-CCNE, Anti-pCCNE1
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选择尺寸
变更视图
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
HE12, monoclonal
Application:
ICC, IP, WB
Citations:
30
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
HE12, monoclonal
species reactivity
human
packaging
antibody small pack of 25 μg
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... CCNE1(898)
General description
细胞周期蛋白 E 是 Cdk2 的调节亚基，在哺乳动物细胞周期中控制 G1/S 的转变。细胞周期蛋白 E 的多种同工型仅在肿瘤中表达，而在正常组织中不表达，这表明细胞周期蛋白 E 受转录后调控。体外分析表明，细胞周期蛋白 E 的这些截短的变体能够磷酸化组蛋白 H1。细胞周期蛋白 E 异常被认为是各种癌症预后较差的指标。
52kda
Immunogen
重组人细胞周期蛋白E
Application
抗细胞周期蛋白 E 抗体，克隆 HE12 是用于检测细胞周期蛋白 E 的高质量小鼠单克隆抗体，&已在 IP、WB、ICC 中进行了验证。
Biochem/physiol Actions
人 p52 周期蛋白 E
Physical form
形式：纯化的
Preparation Note
在 -20°C 下可保存 2 年，在 4°C 下可保存 6 个月
Analysis Note
在人 A431 裂解物中的免疫印迹中进行了常规评估
对照
阳性抗原对照：货号12-301，未刺激的A431细胞裂解液。 加入2.5µL 2-巯基乙醇/100µL裂解液，煮沸5分钟以减少制备量。在微凝胶每个泳道上样20µg经还原的裂解液。
阳性抗原对照：货号12-301，未刺激的A431细胞裂解液。 加入2.5µL 2-巯基乙醇/100µL裂解液，煮沸5分钟以减少制备量。在微凝胶每个泳道上样20µg经还原的裂解液。
Other Notes
替代：04-223
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Maimets, T; Neganova, I; Armstrong, L; Lako, M
Oncogene null
Hae-June Lee et al.
Radiation research, 170(5), 579-590 (2008-10-31)
The aim of this work was to identify specific genes involved in rat mammary tumors induced by dimethylbenz(a)anthracene (DMBA) or radiation. More TUNEL- and PCNA-positive cells were present in mammary tumors induced by radiation than in tumors induced by DMBA
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Tissue regeneration mediated by mesenchymal stem cells (MSCs) is deemed a desirable way to repair teeth and craniomaxillofacial tissue defects. Nevertheless, the molecular mechanisms about cell proliferation and committed differentiation of MSCs remain obscure. Previous researches have proved that lysine
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 05-363-25UG | 04054839350184 |