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抗Rac1抗体，克隆23A8

Name: 抗Rac1抗体，克隆23A8
Brand: MM

clone 23A8, Upstate^®, from mouse

别名:

抗Rac1

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

23A8, monoclonal

Application:

IHC, IP, WB

Citations:

501

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属性

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

23A8, monoclonal

species reactivity

rat, human, mouse

packaging

antibody small pack of 25 μg

manufacturer/tradename

Upstate^®

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG2b

NCBI accession no.

NM_006908

UniProt accession no.

P63000

shipped in

ambient

target post-translational modification

unmodified

Gene Information

human ... RAC1(5879)

说明

General description

21kda

Rac1是RhoGTPase亚家族（Rac1-Rac4）的成员，该亚家族可将来自G偶联蛋白受体（GPCR）、整联蛋白和生长因子受体的细胞外信号转导至调节多种信号通路的效应分子。尽管Rac1支持MAP激酶途径的激活和基因激活，但它’最重要的功能还包括对细胞骨架结构的调节。Rac与Rho（应力纤维的调节子）和Cdc42（丝状伪足的调节子）一起，可调节粘着斑（FA）复合物的形成。膜皱纹和片状脂溢有助于实现与细胞附着和运动有关的重要细胞功能。

Immunogen

包含全长人Rac的重组蛋白

Application

此抗Rac1抗体的23A8克隆已被引用40多次，并已经过验证可用于免疫组织化学（IHC）、免疫沉淀（IP）和蛋白质印迹（WB），以检测Rac1蛋白。

研究子类别
细胞骨架信号转导

G蛋白

研究类别
信号传导

Biochem/physiol Actions

识别Rac1；强烈的Rac1偏好性，略微的Rac2交叉反应性。

Physical form

在蛋白G中纯化的免疫球蛋白，在添加30％甘油之前溶于0.1M Tris-甘氨酸（pH 7.4）、0.15M NaCl、0.05％叠氮化钠中。

形式：纯化

蛋白G纯化

Preparation Note

自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。

Analysis Note

对照
免疫印迹/免疫沉淀：大鼠脑微粒体蛋白制剂
免疫组织化学：大鼠脑切片

已通过免疫印迹对大鼠脑微粒体蛋白的制剂进行常规评估

Other Notes

浓度：请参考批次特异性浓缩物的分析证书。

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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存储类别

10 - Combustible liquids

wgk

WGK 1

法规信息

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货号	GTIN
05-389-25UG	04054839337789