05-446
抗-p75NTR（神经营养因子受体）抗体，克隆ME20.4
clone A16/17, Upstate®, from mouse
别名:
p75 Low Affinity Neurotrophin Receptor, NGFR
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
A16/17, monoclonal
Application:
IHC, IP, Neutral, WB
Citations:
21
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
A16/17, monoclonal
species reactivity
monkey, human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, neutralization: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NGFR(4804)
General description
69kDa
Immunogen
人黑素瘤细胞系WM245。
Application
抗p75NTR（神经营养因子受体）抗体，克隆ME20.4可检测p75NTR（神经营养因子受体）的水平&已发表，&经验证可用于IP、WB、IH、NEUT。
研究子类别
激酶&磷酸酶
神经退行性疾病
激酶&磷酸酶
神经退行性疾病
研究类别
神经科学
神经科学
Biochem/physiol Actions
低亲和p75NTR
Physical form
0.1M Tris-甘氨酸（pH 7.4），0.15M NaCl，0.05％叠氮化钠，然后添加甘油至30％
形式：纯化
蛋白G层析
Preparation Note
在-20°C下可保存2年
Analysis Note
已通过免疫印迹法对HS294T细胞的RIPA裂解液进行了常规评估
Other Notes
替代：04-1111
由于许可协议限制，无法购买该产品进行转售。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
J Du et al.
The Journal of cell biology, 150(6), 1423-1434 (2000-09-20)
Brain-derived neurotrophic factor (BDNF) has been shown to regulate neuronal survival and synaptic plasticity in the central nervous system (CNS) in an activity-dependent manner, but the underlying mechanisms remain unclear. Here we report that the number of BDNF receptor TrkB
S M Mooney et al.
Neuroscience, 149(2), 372-381 (2007-09-18)
Organotypic cultures of rat cortex were used to test the hypotheses that nerve growth factor (NGF) is neuroprotective for immature cortical neurons and that ethanol abolishes this neuroprotection in a developmental stage-dependent manner. Samples were obtained on gestational day (G)
Immuno-electron microscopy characterization of human bone marrow stromal cells with anti-NGFR antibodies.
Caneva, L, et al.
Blood Cells, Molecules and Diseases, 21, 73-85 (1995)
C Dominici et al.
Journal of neuro-oncology, 31(1-2), 57-64 (1997-01-01)
In neuroblastoma, high levels of mRNA for p140trkA and p75LNGFR neurotrophin receptors are predictive of favorable outcome. Their evaluation by Northern blot, however, requires substantial amounts of tissue and this prevents their routine evaluation as well as the possibility for
Low-affinity nerve growth factor receptor immunoreactivity in the human urinary bladder.
Wakabayashi, Y, et al.
Neuroscience Letters, 186, 9-12 (1995)
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