05-486
抗-FADD抗体，克隆1F7
clone 1F7, Upstate®, from mouse
别名:
Anti-GIG3, Anti-IMD90, Anti-MORT1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
1F7, monoclonal
Application:
WB
Species reactivity:
mouse, human
Citations:
39
Technique(s):
western blot: suitable
Uniprot accession no.:
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
1F7, monoclonal
species reactivity
mouse, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... FADD(8772)
mouse ... Fadd(14082)
Analysis Note
对照
阳性抗原对照：目录# 12-303，Jurkat细胞裂解液。
阳性抗原对照：目录# 12-303，Jurkat细胞裂解液。
通过免疫印迹法对Jurkat细胞的RIPA裂解液进行了常规评估
Application
抗FADD抗体，克隆1F7，可检测FADD的水平 & 已出版 & 并经过验证可用于WB。
研究子类别
凋亡-附加
凋亡-附加
研究类别
细胞凋亡 & 癌症
细胞凋亡 & 癌症
Biochem/physiol Actions
FADD
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
28kDa
Immunogen
对应人FADD的GST标记全长融合蛋白
Other Notes
替代：04-1113
Physical form
PBS，pH 7.2和50%甘油
形式：纯化
蛋白A层析
Preparation Note
在-20°C下可保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Suppression of TNF receptor-1 signaling in an in vitro model of epileptic tolerance.
Thompson, SJ; Ashley, MD; Stohr, S; Schindler, C; Li, M; McCarthy-Culpepper, KA; Pearson et al.
International Journal of Physiology, Pathophysiology and Pharmacology null
Hayley I Muendlein et al.
Science (New York, N.Y.), 367(6484), 1379-1384 (2020-03-21)
Cell death and inflammation are interdependent host responses to infection. During pyroptotic cell death, interleukin-1β (IL-1β) release occurs through caspase-1 and caspase-11-mediated gasdermin D pore formation. In vivo, responses to lipopolysaccharide (LPS) result in IL-1β secretion. In vitro, however, murine
Katerina Vlantis et al.
Immunity, 44(3), 553-567 (2016-03-18)
Intestinal epithelial cells (IECs) regulate gut immune homeostasis, and impaired epithelial responses are implicated in the pathogenesis of inflammatory bowel diseases (IBD). IEC-specific ablation of nuclear factor κB (NF-κB) essential modulator (NEMO) caused Paneth cell apoptosis and impaired antimicrobial factor
Eun-Young Ahn et al.
International journal of cancer, 100(4), 445-451 (2002-07-13)
Human cholangiocarcinoma is a malignancy with no effective therapy and a poor prognosis. Previously, we demonstrated that cultured human cholangiocarcinoma cell lines heterogeneously express Fas on their surface, resulting in 2 subpopulations, Fas-high and Fas-low cells. Fas-low cells are resistant
Targeting Bcl-xL in esophageal squamous cancer to sensitize to chemotherapy plus TRAIL-induced apoptosis while normal epithelial cells are protected by blockade of caspase 9.
K Kim et al.
Cell death and differentiation, 11(5), 583-587 (2004-01-31)
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