05-636-AF488
抗磷酸化组蛋白H2A.X (Ser139) ，克隆JBW301，Alexa Fluor™ 488 结合抗体
clone JBW301, from mouse, ALEXA FLUOR™ 488
别名:
Histone H2AX, H2a/x, Histone H2A.X
产品名称
抗磷酸化组蛋白H2A.X (Ser139) ，克隆JBW301，Alexa Fluor™ 488 结合抗体, clone JBW301, from mouse, ALEXA FLUOR™ 488
biological source
mouse
conjugate
ALEXA FLUOR™ 488
antibody form
purified antibody
antibody product type
primary antibodies
clone
JBW301, monoclonal
species reactivity
human
species reactivity (predicted by homology)
vertebrates (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer139)
Quality Level
Gene Information
human ... H2AX(3014)
Analysis Note
通过免疫细胞化学在未处理（阴性对照）和星形孢菌素处理的HeLa细胞中进行评估。
免疫细胞化学分析：来自代表性批次的1:100稀释液在星形孢菌素处理的HeLa细胞中检测到磷酸组蛋白H2A.X（Ser139），而在未处理的HeLa细胞中未检测到。
免疫细胞化学分析：来自代表性批次的1:100稀释液在星形孢菌素处理的HeLa细胞中检测到磷酸组蛋白H2A.X（Ser139），而在未处理的HeLa细胞中未检测到。
Application
该抗磷酸化组蛋白H2A.X（Ser139）抗体（克隆JBW301，Alexa Fluor™ 488偶联物）经验证可用于ICC检测磷酸化组蛋白H2A.X（Ser139）。
General description
组蛋白H2A.X是组蛋白H2A的变体，与基因组DNA相似。但是，组蛋白在结构上与H2A家族的其他成员不同，因为它具有一个C末端尾巴，该尾巴包含Ser139残基，该残基响应于双链DNA的断裂而被磷酸化。H2A.X的磷酸化是由ATM/ATR蛋白介导的快速过程。
计算分子量为17 kDa
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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