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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
1H6, monoclonal
Species reactivity:
vertebrates
Application:
flow cytometry
immunohistochemistry
immunohistochemistry
Technique(s):
flow cytometry: suitable
immunohistochemistry: suitable
immunohistochemistry: suitable
Citations:
40
产品名称
抗磷脂酰丝氨酸抗体,克隆1H6, clone 1H6, Upstate®, from mouse
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1H6, monoclonal
species reactivity
vertebrates
manufacturer/tradename
Upstate®
technique(s)
flow cytometry: suitable
immunohistochemistry: suitable
isotype
IgG
shipped in
dry ice
target post-translational modification
phosphorylation (pSer)
Quality Level
Gene Information
human ... PTDSS1(9791)
Application
抗磷脂酰丝氨酸抗体,克隆1H6是用于FC,IH的抗磷脂酰丝氨酸抗体。
流式细胞术:0.2-2 μg/mL先前批次在用Fas配体囊泡处理的Jurkat细胞上检测到细胞表面磷脂酰丝氨酸(目录号01-210)。见第2页。
免疫组织化学:该抗体已由独立实验室报告用于检测用乙醇/丙酮固定的大鼠颈动脉石蜡切片中的磷脂酰丝氨酸(Mandinov,L.,2003)。
免疫组织化学:该抗体已由独立实验室报告用于检测用乙醇/丙酮固定的大鼠颈动脉石蜡切片中的磷脂酰丝氨酸(Mandinov,L.,2003)。
研究子类别
凋亡-附加
凋亡-附加
研究类别
细胞凋亡 & 癌症
细胞凋亡 & 癌症
Biochem/physiol Actions
识别细胞膜中的磷脂酰丝氨酸(PS)
Analysis Note
对照
脑组织
脑组织
通过流式细胞术对经Fas配体囊泡处理的Jurkat细胞进行常规评估(目录号01-210)
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
意义:
抗磷脂酰丝氨酸可用于检测膜磷脂磷脂酰丝氨酸(PS)从内膜小叶向外膜小叶的移位;它提供了膜联蛋白V的替代方法,用于定量细胞凋亡。
抗磷脂酰丝氨酸可用于检测膜磷脂磷脂酰丝氨酸(PS)从内膜小叶向外膜小叶的移位;它提供了膜联蛋白V的替代方法,用于定量细胞凋亡。
未给出
磷脂酰丝氨酸(PS)是在所有动植物的膜中发现的磷脂(1,2-二酰基-sn-甘油-(3)-L-磷酸丝氨酸)。 PS最集中在大脑中,因为PS约占神经元脂质含量的10%。神经性PS被认为在维持神经细胞完整性、增强神经递质信号效率、改善神经细胞信号传递方面发挥作用。 细胞凋亡的关键特征之一是细胞外膜上PS的表达。 PS通常在质膜的内侧发现,但是在细胞凋亡的早期阶段,PS易位到外膜。FITC标记的膜联蛋白V可以与暴露的PS结合,为大多数基于膜联蛋白V的细胞凋亡测定提供了基础。
Immunogen
含有70%磷脂酰丝氨酸和30%磷脂酰甘油的脂质体
Other Notes
浓度:请参考批次特异性浓缩物的分析证书。
Physical form
形式:纯化
纯化IgG,溶于0.1M Tris-甘氨酸、0.15M NaCl、0.05%叠氮化钠(加30%甘油前)溶液(pH 7.4)。在20°C为液体形式。
蛋白G纯化
Preparation Note
自收到之日起可稳定保存1年。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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