生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
6F-H2, monoclonal
种属反应性
human
制造商/商品名称
Upstate®
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... WT1(7490)
一般描述
55-60kDa
免疫原
6His标记融合蛋白，对应人WT1（维尔姆斯瘤）的1-181位残基。
应用
抗-WT1抗体（克隆6F-H2）是一种用于检测WT1（又称维尔姆斯瘤）的小鼠单克隆抗体，目前已通过WB、ICC & IHC应用验证。
生化/生理作用
WT1
外形
形式：纯化
分析说明
已通过免疫印迹对Jurkat和Raji细胞的RIPA裂解液进行常规评估
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Toru Sakairi et al.
American journal of physiology. Renal physiology, 298(3), F557-F567 (2009-12-04)
Evidence suggests that loss of podocytes into urine contributes to development of glomerular diseases; shed podocytes are frequently viable and proliferate in culture conditions. To determine the phenotypic characteristics of viable urinary cells derived from human subjects, we established long-term
Embryonic Stem Cells Derived Kidney Organoids as Faithful Models to Target Programmed Nephrogenesis.
Zenglai Tan et al.
Scientific reports, 8(1), 16618-16618 (2018-11-11)
The kidney is a complex organ that is comprised of thousands of nephrons developing through reciprocal inductive interactions between metanephric mesenchyme (MM) and ureteric bud (UB). The MM undergoes mesenchymal to epithelial transition (MET) in response to the signaling from
Rebecca Vicente-Steijn et al.
PloS one, 10(9), e0136025-e0136025 (2015-09-22)
Morphological and functional differences of the right and left ventricle are apparent in the adult human heart. A differential contribution of cardiac fibroblasts and smooth muscle cells (populations of epicardium-derived cells) to each ventricle may account for part of the
Kazunori Inoue et al.
The Journal of clinical investigation, 129(3), 1295-1313 (2019-02-19)
We identified 2 genes, histone deacetylase 1 (HDAC1) and HDAC2, contributing to the pathogenesis of proteinuric kidney diseases, the leading cause of end-stage kidney disease. mRNA expression profiling from proteinuric mouse glomeruli was linked to Connectivity Map databases, identifying HDAC1
Chen Wu et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 8(9), 1163-1169 (2013-08-16)
The Wilms' tumor gene (WT1) has been identified as an oncogene in many malignant diseases, and aberrant WT1 expression has been linked to development, progression, and prognosis of non-small-cell lung cancer (NSCLC). We sought to investigate the underlying mechanism of
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