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Merck
CN

05-753

抗-WT1抗体,克隆6F-H2

clone 6F-H2, Upstate®, from mouse

别名:

Anti-AWT1, Anti-GUD, Anti-NPHS4, Anti-WAGR, Anti-WIT-2, Anti-WT-1, Anti-WT33

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
6F-H2, monoclonal
Application:
ICC, IHC, WB
Citations:
25
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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

6F-H2, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... WT1(7490)

General description

55-60kDa

Immunogen

6His标记融合蛋白,对应人WT1(维尔姆斯瘤)的1-181位残基。

Application

抗-WT1抗体(克隆6F-H2)是一种用于检测WT1(又称维尔姆斯瘤)的小鼠单克隆抗体,目前已通过WB、ICC & IHC应用验证。

Biochem/physiol Actions

WT1

Physical form

形式:纯化

Analysis Note

已通过免疫印迹对Jurkat和Raji细胞的RIPA裂解液进行常规评估

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 1


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Kazunori Inoue et al.
The Journal of clinical investigation, 129(3), 1295-1313 (2019-02-19)
We identified 2 genes, histone deacetylase 1 (HDAC1) and HDAC2, contributing to the pathogenesis of proteinuric kidney diseases, the leading cause of end-stage kidney disease. mRNA expression profiling from proteinuric mouse glomeruli was linked to Connectivity Map databases, identifying HDAC1
Rebecca Vicente-Steijn et al.
PloS one, 10(9), e0136025-e0136025 (2015-09-22)
Morphological and functional differences of the right and left ventricle are apparent in the adult human heart. A differential contribution of cardiac fibroblasts and smooth muscle cells (populations of epicardium-derived cells) to each ventricle may account for part of the
Toru Sakairi et al.
American journal of physiology. Renal physiology, 298(3), F557-F567 (2009-12-04)
Evidence suggests that loss of podocytes into urine contributes to development of glomerular diseases; shed podocytes are frequently viable and proliferate in culture conditions. To determine the phenotypic characteristics of viable urinary cells derived from human subjects, we established long-term
Zenglai Tan et al.
Scientific reports, 8(1), 16618-16618 (2018-11-11)
The kidney is a complex organ that is comprised of thousands of nephrons developing through reciprocal inductive interactions between metanephric mesenchyme (MM) and ureteric bud (UB). The MM undergoes mesenchymal to epithelial transition (MET) in response to the signaling from
Caihua Xu et al.
PloS one, 8(8), e68837-e68837 (2013-08-13)
The Wilms' tumor suppressor gene (WT1) has been identified as an oncogene in many malignant diseases such as leukaemia, breast cancer, mesothelioma and lung cancer. However, the role of WT1 in non-small-cell lung cancer (NSCLC) carcinogenesis remains unclear. In this

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