Merck
CN
所有图片(1)

文件

05-920

Sigma-Aldrich

Anti-NR2B Antibody, clone BWJHL

clone BWJHL, Upstate®, from mouse

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所有图片(1)
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

100

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

BWJHL, monoclonal

种属反应性

human, rat

制造商/商品名称

Upstate®

技术

western blot: suitable

同位素/亚型

IgG

NCBI登记号

NM_012574

UniProt登记号

Q13224

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

mouse ... Grin2B(14812)

特异性

NR2B

免疫原

GST fusion protein corresponding to residues 934-1457 of rat NR2B. Clone BWJHL.

应用

Anti-NR2B Antibody, clone BWJHL detects level of NR2B & has been published & validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Neurodegenerative Diseases

质量

routinely evaluated by immunoblot on rat brain microsomal preparations (Catalog#12-144)

目标描述

Mr 180kDa

外形

Protein G Purified
Format: Purified

储存及稳定性

stable 2 years at -20°C from date of shipment

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Brain-derived neurotrophic factor-tyrosine kinase B pathway mediates NMDA receptor NR2B subunit phosphorylation in the supraoptic nuclei following progressive dehydration.
Carre?o, FR; Walch, JD; Dutta, M; Nedungadi, TP; Cunningham, JT
Journal of Neuroendocrinology null
Jackson J Cone et al.
PloS one, 8(3), e58251-e58251 (2013-03-22)
The development of diet-induced obesity (DIO) can potently alter multiple aspects of dopamine signaling, including dopamine transporter (DAT) expression and dopamine reuptake. However, the time-course of diet-induced changes in DAT expression and function and whether such changes are dependent upon
Peter D Cole et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 19(16), 4446-4454 (2013-07-09)
To test whether memantine can prevent methotrexate-induced cognitive deficits in a preclinical model. After noting that methotrexate exposure induces prolonged elevations of the glutamate analog homocysteic acid (HCA) within cerebrospinal fluid, we tested whether intrathecal injection of HCA would produce
Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington disease.
Li, Lijun, et al.
Neurobiology of Aging, 24, 1113-1121 (2003)
R A J McIlhinney et al.
Biochemical Society transactions, 31(Pt 4), 865-868 (2003-07-31)
The N-methyl-D-aspartate receptor (NMDAR) requires both NR1 and NR2 subunits to form a functional ion channel. Despite the recent advances in our understanding of the contributions of these different subunits to both the function and pharmacology of the NMDAR, the
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