06-225
抗-c-Jun抗体
serum, Upstate®
别名:
Activator protein 1, AP1, p39, Proto-oncogene c-Jun, Transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog
登录 查看组织和合同定价。
选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Species reactivity:
human, avian, mouse
Citations:
23
Technique(s):
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗-c-Jun抗体, serum, Upstate®
biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, avian, mouse
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... JUN(3725)
mouse ... Jun(16476)
Analysis Note
对照
阳性抗原对照：目录# 12-303，Jurkat细胞裂解液。
阳性抗原对照：目录# 12-303，Jurkat细胞裂解液。
已通过免疫印迹对人A431细胞或Jurkat细胞裂解液的RIPA裂解液进行了常规评估
Application
用抗c-Jun兔多克隆抗血清（目录号06-225）检测c-Jun（又称转录因子AP-1），已被证明可用于免疫细胞化学，免疫沉淀和蛋白质印迹。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
c-Jun
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
35-39 kDa
c-Jun是转录因子AP-1的一部分，可结合并激活TRE/AP-1元件上的转录，并且似乎是SAPK/JNK信号通路的主要下游靶标。c-Jun的转录活性受Ser63和Ser73的磷酸化的调节。胞外信号（包括生长因子、转化癌蛋白和紫外线照射）刺激c-Jun在Ser63/73处的磷酸化并激活c-Jun依赖性转录。Ser63/73的突变使c-Jun对有丝分裂和应激诱导的
信号通路无反应。MAP激酶的同系物，SAPK/JNK，与c-Jun的N端结合，并在Ser63/73处磷酸化c-Jun。此外，激活c-Jun的信号同样也刺激SAPK/JNK的活性。
信号通路无反应。MAP激酶的同系物，SAPK/JNK，与c-Jun的N端结合，并在Ser63/73处磷酸化c-Jun。此外，激活c-Jun的信号同样也刺激SAPK/JNK的活性。
Immunogen
含有禽c-Jun DNA结合域的Trp E融合蛋白
Other Notes
替代：04-210
Physical form
全兔抗血清，含0.05％叠氮化钠
抗血清
Preparation Note
在-20°C下可保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
Multiple mitogen-activated protein kinases are regulated by hyperosmolality in mouse IMCD cells.
T Berl, G Siriwardana, L Ao, L M Butterfield, L E Heasley, T Berl, G Siriwardana, L Ao et al.
The American Journal of Physiology null
Characterization of the chromosomal binding sites and dimerization partners of the viral oncoprotein Meq in Marek's disease virus-transformed T cells.
Alon M Levy, Yoshihiro Izumiya, Peter Brunovskis, Liang Xia, Mark S Parcells et al.
Journal of virology null
The oncogenic microRNA OncomiR-21 overexpressed during Marek's disease lymphomagenesis is transactivated by the viral oncoprotein Meq.
Stik, G; Dambrine, G; Pfeffer, S; Rasschaert, D
Journal of virology null
Myristylation alters DNA-binding activity and transactivation of FBR (gag-fos) protein
Kamata, N., et al
Molecular and cellular biology, 11, 765-772 (1991)
Steffen Klippel et al.
British journal of haematology, 159(3), 340-351 (2012-09-14)
Jasmonates, plant stress hormones, have been demonstrated to be effective in killing various types of cancer cells. We therefore tested if methyljasmonate (MJ) has activity against multiple myeloma (MM) in vitro and in vivo. MM cell lines and primary MM
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持