06-852
抗-Spinophilin/Neurabin-II抗体
Upstate®, from rabbit
别名:
Protein phosphatase 1 regulatory subunit 9B 3 neurabin II, protein phosphatase 1, regulatory (inhibitor) subunit 9B, protein phosphatase 1, regulatory subunit 9B, protein phosphatase 1, regulatory subunit 9B, spinophilin
产品名称
抗-Spinophilin/Neurabin-II抗体, Upstate®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PPP1R9B(84687)
Analysis Note
对照
脑组织
脑组织
已通过蛋白免疫印迹对大鼠脑微粒体制剂进行了常规评估。
蛋白质印迹分析：
0.25-1 μg/mL该批次产品已在20 μg大鼠脑微粒体制剂（目录号12-144）中检测到Spinophilin/Neurabin-II。
蛋白质印迹分析：
0.25-1 μg/mL该批次产品已在20 μg大鼠脑微粒体制剂（目录号12-144）中检测到Spinophilin/Neurabin-II。
Application
免疫沉淀：
4 μg的先前批次对来自500 μg大鼠脑微粒体制剂（目录号12-144）的Spinophilin/Neurabin-II进行免疫沉淀。
4 μg的先前批次对来自500 μg大鼠脑微粒体制剂（目录号12-144）的Spinophilin/Neurabin-II进行免疫沉淀。
抗Spinophilin/Neurabin-II抗体是一种针对Spinophilin/Neurabin-II的抗体，可用于IC、IP & WB。
研究子类别
突触 & 突触生物学
神经元 & 胶质标记
突触 & 突触生物学
神经元 & 胶质标记
研究类别
神经科学
神经科学
Biochem/physiol Actions
其他物种未知。
特异于spinophilin，Mr 120 kDa。也可识别疑似为spinophilin（Mr 95kDa）裂解产物的条带。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
120 kDa
Spinophilin/neurabin II是一种肌动蛋白相关的支架蛋白，富含神经元的树突棘。
Immunogen
GST融合蛋白，对应人脑Spinophilin/Neurabin-II的286-390位残基。
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
形式：纯化
纯化的兔多克隆IgG，溶于含有70%储存缓冲液（0.014 M 磷酸盐缓冲液（pH 7.6）、0.175 M NaCl、0.07％叠氮化钠）和30％甘油的缓冲液中。储存于 -20°C。
蛋白G纯化
Preparation Note
自收到之日起在-20ºC可稳定保存1年。
处理建议：
收到后，在取下瓶盖之前，将小瓶离心并轻轻混合溶液。分装到微量离心管中，并储存于 -20°C。避免反复冻融，其可能会破坏IgG并影响产品性能。注意：冷藏室温度变化至低于-20°C时可能导致含甘油的溶液在储存过程中冻结。
处理建议：
收到后，在取下瓶盖之前，将小瓶离心并轻轻混合溶液。分装到微量离心管中，并储存于 -20°C。避免反复冻融，其可能会破坏IgG并影响产品性能。注意：冷藏室温度变化至低于-20°C时可能导致含甘油的溶液在储存过程中冻结。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
A Satoh et al.
The Journal of biological chemistry, 273(6), 3470-3475 (1998-03-07)
In a preceding paper, we reported a novel actin filament (F-actin)-binding protein, named neurabin, which was specifically expressed in neural tissue and implicated in neurite formation. We purified from rat brain another F-actin-binding protein, which had a domain organization similar
Age-related changes in Usp9x protein expression and DNA methylation in mouse brain.
Jun Xu
Brain Research Molecular Brain Research null
Ryan T Terry-Lorenzo et al.
The Journal of biological chemistry, 277(48), 46535-46543 (2002-09-25)
Inhibitor-2 (I-2) bound protein phosphatase-1 (PP1) and several PP1-binding proteins from rat brain extracts, including the actin-binding proteins, neurabin I and neurabin II. Neurabins from rat brain lysates were sedimented by I-2 and its structural homologue, I-4. The central domain
Bridget M Nugent et al.
Nature neuroscience, 18(5), 690-697 (2015-03-31)
The developing mammalian brain is destined for a female phenotype unless exposed to gonadal hormones during a perinatal sensitive period. It has been assumed that the undifferentiated brain is masculinized by direct induction of transcription by ligand-activated nuclear steroid receptors.
Interaction of rat lin-10 with brain-enriched F-actin-binding protein, neurabin-II/spinophilin.
Ide, N, et al.
Biochemical and biophysical research communications, 244, 258-262 (1998)
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