biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
hamster, bovine, rat, pig, mouse, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TYRO3(7301)
General description
41kDa
Immunogen
基于PKA催化亚基的人41kDaα同工型氨基酸8-22的肽（KKGSEQESVKEFLAK-C）
Application
抗PDGF中和抗体，可检测PDGF的水平&已有相关文献发布 & 通过蛋白质印迹验证。
研究子类别
细胞骨架信号转导
细胞骨架信号转导
研究类别
信号传导
信号传导
Biochem/physiol Actions
PKA，PKA重组人α同工型
Physical form
0.1M Tris-甘氨酸，pH 7.4，0.15M NaCl，0.05％叠氮化钠，然后添加甘油至30％
形式：纯化
蛋白A层析
Preparation Note
在-20°C下可保存2年
Analysis Note
通过免疫印迹法对大鼠脑微粒体制备物或PC-12 RIPA细胞裂解液进行了常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
Zhaoqing Zheng et al.
Journal of neurophysiology, 101(5), 2539-2549 (2009-03-06)
The cyclic AMP-dependent protein kinase (PKA) signaling pathway has been shown to be important in mechanisms of synaptic plasticity, although its direct and downstream signaling effects are not well understood. Using an in vitro model of eyeblink classical conditioning, we
Ho-Lin Chuang et al.
Environmental toxicology, 36(9), 1873-1879 (2021-06-06)
Epimedium, is used traditionally in Chinese medicine to treat infertility problems. In this study, we establish the cell model to elucidate the protective effect of epimedium against ES by analyzing the molecular relationship between mitochondrial dynamics and steroidogenesis and to
The Chinese herbal medicine Dai-Zong-Fang promotes browning of white adipocytes in vivo and in vitro by activating PKA pathway to ameliorate obesity.
Xu, et al.
Frontiers in Pharmacology, 14, 1176443-1176443 (2023)
Wanxu Guo et al.
Biology open, 10(5) (2020-10-14)
Podocytes are the major target in proteinuric kidney diseases such as diabetic nephropathy. The underlying molecular mechanisms by which high glucose (HG) results in podocyte damage remain unclear. This study investigated the regulatory role of Smad3, ezrin, and protein kinase
Federica Valsecchi et al.
Journal of cell science, 130(21), 3713-3727 (2017-09-03)
cAMP regulates a wide variety of physiological functions in mammals. This single second messenger can regulate multiple, seemingly disparate functions within independently regulated cell compartments. We have previously identified one such compartment inside the matrix of the mitochondria, where soluble
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