产品名称
抗磷酸化PKR (Thr446) 抗体, Upstate®, from rabbit
biological source
rabbit
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pThr446)
Quality Level
Gene Information
human ... EIF2AK2(5610)
相关类别
Analysis Note
通过免疫印迹对HeLa细胞的RIPA裂解液进行了常规评估，HeLa细胞以IFN-α刺激过夜，然后以花萼海绵体诱癌素（calyculin）处理15分钟。
Application
抗磷酸化Brk（Thr446）抗体是针对磷酸化PKR（Thr446）的抗体，可用于WB。
研究子类别
细胞骨架信号转导
细胞骨架信号转导
研究类别
信号传导
信号传导
Biochem/physiol Actions
磷酸化PKR
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
68 kDa
Immunogen
对应于人PKR的Thr446周围氨基酸的肽
Physical form
0.1M Tris-甘氨酸，pH 7.4，0.15M NaCl，0.05％叠氮化钠，然后添加甘油至30％
形式：纯化
纯化蛋白A
Preparation Note
在-20°C下可保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
X Saelens et al.
The Journal of biological chemistry, 276(45), 41620-41628 (2001-09-14)
The protein kinase PKR is a major player in the cellular antiviral response, acting mainly by phosphorylation of the alpha-subunit of the eukaryotic translation initiation factor 2 (eIF2-alpha) to block de novo protein synthesis. PKR activation requires binding of double-stranded
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