biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... FARSB(10056)
General description
42 kDa
Immunogen
对应于人MAP激酶磷酸酶1（MKP1）氨基酸87-101（DERSAALDGAKRDGT-C）的肽
Application
抗MKP1抗体经过验证可用在WB中检测MKP1。
研究子类别
激酶 & 磷酸酶
激酶 & 磷酸酶
研究类别
信号传导
信号传导
Biochem/physiol Actions
识别MKP1。
Physical form
形式：纯化
蛋白A纯化
蛋白A纯化的免疫球蛋白，溶于30％甘油，0.07M Tris-甘氨酸（pH 7.4）、0.105 M NaCl，0.035％叠氮化钠作为防腐剂的溶液中。
Preparation Note
自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。
Analysis Note
对照
阳性抗原对照：目录号12-305，3T3/A31裂解液。加入2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原样本。在微凝胶每个泳道上样20 μg经还原的裂解液。
阳性抗原对照：目录号12-305，3T3/A31裂解液。加入2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原样本。在微凝胶每个泳道上样20 μg经还原的裂解液。
已通过免疫印迹法对3T3/A31细胞的RIPA裂解液进行了常规评估
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
C F Zheng et al.
The Journal of biological chemistry, 268(22), 16116-16119 (1993-08-05)
The activation of extracellular signal-regulated kinase (ERK) or mitogen-activated protein kinase (MAPK) by a dual specific kinase, MEK (MAPK or ERK kinase), is a critical event in the mitogenic signal transduction pathway. However, little is known about the mechanism of
Epinephrine and AICAR-induced PGC-1? mRNA expression is intact in skeletal muscle from rats fed a high-fat diet.
Frier, BC; Wan, Z; Williams, DB; Stefanson, AL; Wright, DC
American Journal of Physiology. Cell Physiology null
Marina Lasa et al.
Molecular and cellular biology, 22(22), 7802-7811 (2002-10-23)
The stress-activated protein kinase p38 stabilizes a number of mRNAs encoding inflammatory mediators, such as cyclooxygenase 2 (Cox-2). In HeLa cells the anti-inflammatory glucocorticoid dexamethasone destabilizes Cox-2 mRNA by inhibiting p38 function. Here we demonstrate that this effect is phosphatase