生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human, chicken
制造商/商品名称
Upstate®
技术
inhibition assay: suitable (peptide)
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
dimethylation (Arg2)
基因信息
human ... H3F3B(3021)
一般描述
Mr 17kDa
免疫原
一种含有序列AdimRT的肽，对应于人组蛋白H3的二甲基-精氨酸2
应用
抗二甲基化组蛋白H3（Arg2）抗体是一种兔多克隆抗体，用于检测二甲基化组蛋白H3（Arg2），也称为H3R2me2，组蛋白H3（二甲基R2），& 已在WB，PIA中进行了验证。
研究子类别
组蛋白
组蛋白
研究类别
表观遗传学&核功能
表观遗传学&核功能
生化/生理作用
组蛋白H3残基2的二甲基精氨酸
预计具有广泛的物种交叉反应性
外形
兔抗血清，含有0.05%叠氮化钠，然后添加甘油至30%
血清
制备说明
在-20°C下可保存2年
分析说明
通过免疫印迹法对鸡红细胞（目录号13-107）的酸提取蛋白进行常规评估
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Jihee Hong et al.
Journal of ginseng research, 46(3), 481-488 (2022-05-24)
Although the tumor-suppressive effects of ginsenosides in cell cycle have been well established, their pharmacological properties in mitosis have not been clarified yet. The chromosomal instability resulting from dysregulated mitotic processes is usually increased in cancer. In this study, we
PELP1 oncogenic functions involve alternative splicing via PRMT6.
Mann, M; Zou, Y; Chen, Y; Brann, D; Vadlamudi, R
Molecular Oncology null
Claudia Stein et al.
Nucleic acids research, 40(19), 9522-9533 (2012-08-21)
The protein arginine methyltransferase 6 (PRMT6) is a coregulator of gene expression and executes its repressing as well as activating function by asymmetric dimethylation of histone H3 at R2 (H3 R2me2a). Given that elevated expression levels of PRMT6 have been
Sinja Rakow et al.
Methods (San Diego, Calif.), 175, 53-65 (2019-09-23)
Among the widespread and increasing number of identified post-translational modifications (PTMs), arginine methylation is catalyzed by the protein arginine methyltransferases (PRMTs) and regulates fundamental processes in cells, such as gene regulation, RNA processing, translation, and signal transduction. As epigenetic regulators
Francesca Chignola et al.
Nucleic acids research, 37(9), 2951-2961 (2009-03-19)
Plant homeodomain (PHD) fingers are often present in chromatin-binding proteins and have been shown to bind histone H3 N-terminal tails. Mutations in the autoimmune regulator (AIRE) protein, which harbours two PHD fingers, cause a rare monogenic disease, autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
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