产品名称
抗-二甲基精氨酸抗体，非对称性（ASYM25）, serum, from rabbit
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse
species reactivity (predicted by homology)
rat (based on 100% sequence homology), human (based on 100% sequence homology)
technique(s)
western blot: suitable
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Analysis Note
对照
经PRMT1处理和未处理的MEF细胞裂解液
经PRMT1处理和未处理的MEF细胞裂解液
已通过蛋白质印迹法在经PRMT1处理和未经处理的MEF细胞裂解液中进行了评估。
蛋白质印迹分析：该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。
蛋白质印迹分析：该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。
Application
使用经验证可用于WB的不对称性抗二甲基精氨酸抗体（ASYM25）检测二甲基精氨酸。
Biochem/physiol Actions
该抗体可识别二甲基化精氨酸。
General description
不对称二甲基化精氨酸（ADMA）是一种内源性L-精氨酸代谢产物，由含有甲基化精氨酸的蛋白质的蛋白水解产生，并且是一氧化氮合酶（NOS）的已知抑制剂。在各种研究中，已经观察到ADMA在细胞运动和肌动蛋白细胞骨架中具有调节作用。ADMA水平升高与散发性FSGS、冠状动脉疾病、高血压、外周动脉闭塞性疾病、肥胖、卒中、先兆子痫和糖尿病肾病患者的心血管死亡率/发病率相关。
多个。 该抗体可检测含有不对称二甲基化精氨酸的蛋白质。
Immunogen
含有不对称二甲基-精氨酸-甘氨酸重复序列的KLH偶联线性肽。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
Li-Ming Liu et al.
Cancer research, 79(11), 2865-2877 (2019-04-25)
C/EBPα is an essential transcription factor involved in regulating the expression or function of certain cell-cycle regulators, including in breast cancer cells. Although protein arginine methyltransferases have been shown to play oncogenic roles in a variety of cancers, little is
Li-Ming Liu et al.
Life (Basel, Switzerland), 11(8) (2021-08-28)
The protein p53 is one of the most important tumor suppressors, responding to a variety of stress signals. Mutations in p53 occur in about half of human cancer cases, and dysregulation of the p53 function by epigenetic modifiers and modifications
Yongtai Bai et al.
Molecular cell, 75(6), 1299-1314 (2019-07-30)
MRE11 nuclease forms a trimeric complex (MRN) with RAD50 and NBS1 and plays a central role in preventing genomic instability. When DNA double-strand breaks (DSBs) occur, MRN is quickly recruited to the damage site and initiates DNA end resection; accordingly
Minghao Yang et al.
Cell death & disease, 13(9), 815-815 (2022-09-24)
Osteosarcoma (OS), the most common primary malignancy of the bone, has a poor prognosis due to its high mortality rate and high potential for metastasis. Thus, it is urgently necessary to explore functional molecular targets of therapeutic strategies for osteosarcoma.
Gang Ren et al.
Scientific reports, 9(1), 6688-6688 (2019-05-02)
One third of newly diagnosed breast cancers in the US are early-stage lesions. The etiological understanding and treatment of these lesions have become major clinical challenges. Because breast cancer risk factors are often linked to aberrant nitric oxide (NO) production
相关内容
Signaling Product Guide: Antibodies, small molecule inhibitors, kits, assays and proteins for signaling research.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持