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1.00662

山梨酸

EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, NF, FCC, E 200

别名:

Sorbic acid, 2,4-Hexadienic acid

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关于此项目

经验公式（希尔记法）:
C6H8O2
化学文摘社编号:
110-44-1
分子量:
112.13
UNSPSC Code:
12352106
E Number:
E200
EC Index Number:
203-768-7
MDL number:
MFCD00002703
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Quality Level

500

agency

BP, ChP, NF, Ph. Eur.

reg. compliance

FCC

vapor pressure

0.00018 hPa ( 20 °C)

product line

EMPROVE® ESSENTIAL

assay

99.0-101.0% substance (anhydrous) basis (acidimetric)

form

solid

autoignition temp.

>130 °C

technique(s)

API processing | cocrystal formation: suitable, API processing | salt formation: suitable

pH

3.3 (20 °C, 1.6 g/L in H2O)

bp

160-260 °C/1013 hPa (decomposition)

mp

120-150 °C

solubility

1.6 g/L

density

1.2 g/cm3 at 20 °C

cation traces

As: ≤0.0003%, Cd: ≤0.001%, Cu: ≤0.001%, Hg: ≤0.0001%, Pb: ≤0.0002%, Zn: ≤0.001%, heavy metals (as Pb): ≤0.0010%

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

SMILES string

OC(=O)\C=C\C=C\C

InChI

1S/C6H8O2/c1-2-3-4-5-6(7)8/h2-5H,1H3,(H,7,8)/b3-2+,5-4+

InChI key

WSWCOQWTEOXDQX-MQQKCMAXSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sorbic acid is commonly used as a preservative in pharmaceutical formulations and cosmetics. It is also used as additive for the preservation of food.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to the US EPA′s Federal Insecticide Fungicide and Rodenticide Act, the European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR), and others.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

flash_point_f

260.6 °F - closed cup

flash_point_c

127 °C - closed cup

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Improving API Solubility using API Processing

Instead of addressing API solubility during formulation, tackle it early during development. Read about the various methods for API processing.

全球贸易项目编号

货号GTIN
100662902504022536008844
100662500004022536008820