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Merck
CN

1.00803

L(+)-Tartaric acid

powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, NF, E 334

别名:

L(+)-Tartaric acid, 2,3-Dihydroxybutanedioic acid

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关于此项目

线性分子式:
HOOCCH(OH)CH(OH)COOH
化学文摘社编号:
分子量:
150.09
UNSPSC Code:
12352106
E Number:
E334
EC Index Number:
201-766-0
MDL number:
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SMILES string

[O-]C(=O)C(O)C(O)C(=O)[O-].[H+].[H+]

InChI

1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)

InChI key

FEWJPZIEWOKRBE-UHFFFAOYSA-N

agency

BP, ChP, JP, NF, Ph. Eur.

vapor pressure

<5 Pa ( 20 °C)

product line

EMPROVE® ESSENTIAL

assay

99.7-100.5% dry basis (acidimetric)

form

powder

autoignition temp.

425 °C

technique(s)

API processing | cocrystal formation: suitable, API processing | salt formation: suitable

pH

1.6 (25 °C, 100 g/L in H2O)

mp

168-170 °C

transition temp

flash point 210 °C

solubility

1390 g/L

density

1.76 g/cm3 at 20 °C

bulk density

1000 kg/m3

cation traces

As: ≤0.0001%, Ca: ≤0.0200%, Ca:, passes test, Hg: ≤0.0001%, Pb: ≤0.0002%, heavy metals (as Pb): ≤0.0010%

application(s)

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

Quality Level

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Tartaric acid is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, tartaric acid has been used primarily as a pH modifier, and in the production of effervescent formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup


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商品

Instead of addressing API solubility during formulation, tackle it early during development. Read about the various methods for API processing.

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