1.00886
4-羟基苯甲酸乙酯钠盐
EMPROVE® ESSENTIAL, Ph. Eur., BP, NF
别名:
Ethyl 4-hydroxybenzoate sodium salt, p-Hydroxybenzoic acid ethyl ester sodium salt, Ethylparaben sodium salt
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关于此项目
经验公式（希尔记法）:
C9H9NaO3
化学文摘社编号:
分子量:
188.16
MDL number:
UNSPSC Code:
12352108
EC Index Number:
252-487-6
Quality Segment
agency
BP, NF, Ph. Eur.
product line
EMPROVE® ESSENTIAL
form
solid
pH
10 (20 °C, 1 g/L in H2O)
bp
297 °C/1013 hPa (free ester,decomposition)
mp
>115 °C (free ester)
transition temp
flash point 121 °C
solubility
1000 g/L
application(s)
liquid formulation
ophthalmics
pharmaceutical
storage temp.
15-25°C
SMILES string
[Na+].[O-]c1ccc(cc1)C(=O)OCC
InChI
1S/C9H10O3.Na/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6,10H,2H2,1H3;/q;+1/p-1
InChI key
QYNMSPKSYXPZHG-UHFFFAOYSA-M
General description
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard ethyl 4-hydroxybenzoate.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
The product is not intended for use as a biocide under global biocide regulations, including but not limited to the US EPA′s Federal Insecticide Fungicide and Rodenticide Act, the European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR), and others.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
249.8 °F
flash_point_c
121 °C
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