产品名称
Cellvento® ModiFeed Gal- COMP, Chemically defined, CHO fed-batch feed for galactosylation reduction, EMPROVE® CCM
Quality Segment
biological source
non-animal source
description
shipped with cooling packs
product line
Cellvento®
form
compacted dry powder
greener alternative product characteristics
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
cell culture | mammalian: suitable
application(s)
pharma/biopharma processes
components
glucose: no
greener alternative category
storage temp.
2-8°C
General description
Cellvento®ModiFeed Gal- COMP is a chemically defined, animal-component-free cell culture feed developed for CHO fed-batch bioprocessing and targeted control of terminal galactosylation. As part of the Cellvento® ModiFeed platform, this highly concentrated, compacted dry powder is a complete, single-part, pH-neutral feed that replenishes essential nutrients while supporting increased G0(F) and reduced G1(F)/G2(F) glycan levels. The formulation contains no glucose, hydrolysates, phenol red, or 2-mercaptoethanol (2-ME), helping simplify feed preparation and process integration. On combination with Cellvento®ModiFeed Prime it allows tunable galactosylation.
Cellvento® ModiFeed Gal- COMP is supported by the Emprove® Program and designated DfS, making it suitable for scalable, quality-focused biologics manufacturing workflows.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.
Cellvento® ModiFeed Gal- COMP is supported by the Emprove® Program and designated DfS, making it suitable for scalable, quality-focused biologics manufacturing workflows.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.
Application
Cellvento® ModiFeed Gal- COMP Suitable for
- CHO-based mAb & biosimilar development and commercial manufacturing
- Fed-batch bioprocessing requiring reduced terminal galactosylation (↑G0F, ↓G1F/G2F)
- Process intensification via high-concentration, reduced-volume feedingGlycosylation tuning in combination with Cellvento® ModiFeed Prime COMP
- CHO suspension cell lines including CHO-S, CHO-DHFR⁻, CHO-K1, CHO-GS, and CHOZN®
- Compatible with Cellvento® 4CHO COMP and EX-CELL® Advanced CHO production media for a fully integrated, chemically defined upstream process platform
Features and Benefits
- One-part, pH-neutral complete feed for simplified fed-batch process
- Maximizes terminal galactosylation without compromising titer
- Highly concentrated to reduce feed volume added to bioreactor
- Compacted powder for convenient handling and easy hydration
- Ambient-stable hydrated solution up to 30 days
- Chemically defined, no animal-origin components
- No glucose enabling precise glucose control
- Supported by EMPROVE® CCM Program
Preparation Note
Formulated to contain 143.6 grams of powder per liter of feed.
Legal Information
CHOZN is a registered trademark of Merck KGaA, Darmstadt, Germany
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
11 - Combustible Solids
wgk
WGK 3
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