104662
Cellvento® ModiFeed Sial+ COMP
Chemically defined, CHO fed-batch feed to maximize sialylation, Emprove® CCM
更环保的选择
别名:
CD Animal-Free Fed-Batch Supplement, Cellvento® ModiFeed Sial+, High Sialylation CHO Feed, Sialylation Modulation Feed, Sialylation-Increasing CHO Feed, Terminal Sialylation Feed
登录并加购，请在购物车里查看协议价、货期和发货地。
选择规格
变更视图
关于此项目
UNSPSC Code:
41106213
Quality Segment
biological source
non-animal source
description
shipped with cooling packs
product line
Cellvento®
form
dry powder
greener alternative product characteristics
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
cell culture | mammalian: suitable
application(s)
pharma/biopharma processes
components
glucose: no
greener alternative category
storage temp.
2-8°C
General description
Cellvento® ModiFeed Sial+ COMP is a chemically defined, non-animal origin, complete cell culture feed EMPROVE®CCM supplied as a compacted dry powder for simplified handling and rapid hydration. It is Part of the ModiFeed glycosylation-modulating feed platform, this highly concentrated, single-part, pH-neutral fed-batch feed is engineered to maximize sialylation on the therapeutic protein of interest a critical quality attribute (CQA) directly influencing the biological activity, solubility, serum half-life, and safety of therapeutic glycoproteins.On combination with Cellvento® ModiFeed Prime it allows tunable Sialylation.
Cellvento® ModiFeed Sial+ COMPsupported by the Emprove® Program and designated DfS, making it suitable for scalable, quality-focused biologics manufacturing workflows.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.
Cellvento® ModiFeed Sial+ COMPsupported by the Emprove® Program and designated DfS, making it suitable for scalable, quality-focused biologics manufacturing workflows.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.
Application
Cellvento® ModiFeed Sial+ COMP is used for:
- Monoclonal antibody (mAb) development and commercial biopharmaceutical manufacturing in CHO cell-based expression systems
- Biosimilar development requiring precise, titratable sialylation profile control to match originator glycan fingerprints
- Upstream fed-batch and intensified fed-batch bioprocessing where maximized terminal sialylation is a defined CQA
- Next-generation therapeutic glycoprotein production targeting enhanced anti-inflammatory activity, stability, and efficacy
- Mixed feed glycosylation tuning mcombinable with Cellvento® ModiFeed Prime COMP to dial in a precise target sialylation level across a titratable spectrum
- Compatible with Cellvento® 4CHO COMP and EX-CELL® Advanced CHO production media for a fully integrated, chemically defined upstream CHO bioprocess platform
Features and Benefits
- Complete feed engineered to maximize sialylation
- One-part, pH-neutral complete feed for simplified fed-batch process
- Maximizes terminal galactosylation without compromising titer
- Highly concentrated to reduce feed volume added to bioreactor
- Compacted powder for convenient handling and easy hydration
- Ambient-stable hydrated solution up to 30 days
- Chemically defined, no animal-origin components
- No glucose enabling precise glucose control
- Supported by EMPROVE® CCM Program
Preparation Note
Formulated to contain 155.8 grams of powder per liter of feed.
Legal Information
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
使用 Emprove® 计划保持符合 GMP 要求
使用Emprove® Dossiers可加快资格认证、保持合规性并节省时间。
下载 Dossiers
注意：您将进入 EmproveSuite.com。您的用户名和密码与 SigmaAldrich.com 是分开的，可能不同。
免费注册，几分钟内即可访问 Emprove® Dossiers。 升级您的订阅计划，解锁 Emprove® Suite 中的高级定制内容。
没有找到您要找的内容？访问 Emprove® 计划帮助页面。