质量水平
描述
shipped with cooling packs
产品线
Cellvento®
表单
dry powder
环保替代产品特性
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
技术
cell culture | mammalian: suitable
环保替代产品分类
储存温度
2-8°C
一般描述
Cellvento® ModiFeed Sial+ COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously maximizing sialylation on the protein of interest. It is recommended combination with the production media Cellvento® 4CHO and EX-CELL® Advanced CHO or other production media.
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应用
Control of protein glycosylation, such as sialylation, while maximizing productivity is key for successful therapeutic protein development and production. N-glycoslyations of IgG Fc, particularly sialylation, has been reported to exert significant anti-inflammatory effects. High sialylation levels can help to increase stability, safety, and efficacy of the protein of interest. Cellvento® ModiFeed Sial+ COMP was developed to increase sialylation while maintaining or improving titer in CHO fed-batch processes
特点和优势
- Reduced complexity in fed-batch process
- Complete feed maximizing galactosylation
- Highly concentrated to reduce required feed volume
- Compacted format for conventient handling
- Higher liquid feed stability at room temperature
制备说明
Formulated to contain 155.8 grams of powder per liter of feed.
法律信息
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
法规信息
新产品
商品
Ensure reliable cell culture media supply with our continuously expanding global network of regional sites for resilient biopharma manufacturing.
Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion
相关内容
Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.
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