产品名称
Cellvento® ModiFeed Gal+ COMP, Chemically defined cell culture feed- EMPROVE® CCM, compacted dry powder
Quality Segment
description
shipped with cooling packs
product line
Cellvento®
form
compacted dry powder
greener alternative product characteristics
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
cell culture | mammalian: suitable
application(s)
pharma/biopharma processes
greener alternative category
storage temp.
2-8°C
General description
Cellvento® ModiFeed Gal+ COMP is part of the ModiFeed platform for process optimization in fed-batch. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously maximizing galactosylation on the protein of interest. It is recommended in combination with the production media Cellvento® 4CHO and EX-CELL® Advanced CHO Fed-batch medium or other production media.
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Application
Glycosylation is known to have effects on the biological activity, solubility, serum half-life, and saftey of therapeutic proteins. Control of protein glycosylation processes, such as galactosylation, while maximizing productivity is key for successful mAb process development and production. Cellvento® ModiFeed Gal+ COMP was developed to increase galactosylation while maintaining or improving titer in CHO fed-batch processes.
Features and Benefits
- Reduced complexity in fed-batch process
- Complete feed maximizing galactosylation
- Highly concentrated to reduce required feed volume
- Compacted format for conventient handling
- Higher liquid feed stability at room temperature
Preparation Note
Formulated to contain 159.9 grams of powder per liter of feed.
Legal Information
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
11 - Combustible Solids
wgk
WGK 3
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