产品名称
Cellvento® ModiFeed Gal+ COMP, Chemically defined, CHO fed-batch feed to increase galactosylation, EMPROVE® CCM
Quality Segment
biological source
non-animal source
description
shipped with cooling packs
product line
Cellvento®
form
compacted dry powder
greener alternative product characteristics
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
cell culture | mammalian: suitable
application(s)
pharma/biopharma processes
components
glucose: no
greener alternative category
storage temp.
2-8°C
General description
Cellvento® ModiFeed Gal+ COMP is a chemically defined, animal-origin-free, highly concentrated fed-batch feed designed to maximize galactosylation of monoclonal antibodies (mAbs) and recombinant proteins in CHO cell-based expression systems. Part of the Cellvento® ModiFeed platform, this one-part, pH-neutral feed is supplied as a compacted dry powder. The formulation contains no glucose, no hydrolysates, no phenol red, and no 2-mercaptoethanol, ensuring high batch-to-batch consistency and process control. On combination with Cellvento® ModiFeed Prime it allows tunable galactosylation.
Cellvento® ModiFeed Gal+ COMP supported by the Emprove® Program and designated DfS, making it suitable for scalable, quality-focused biologics manufacturing workflows.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.
Cellvento® ModiFeed Gal+ COMP supported by the Emprove® Program and designated DfS, making it suitable for scalable, quality-focused biologics manufacturing workflows.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.
Application
Cellvento® ModiFeed Gal+ COMP is used for:
- Maximizing galactosylation of mAbs and recombinant proteins in CHO fed-batch processes, while maintaining or improving product titer
- Controlling protein glycosylation, a critical quality attribute affecting biological activity, solubility, serum half-life, and safety of therapeutic proteins
- Targeting specific galactosylation profiles when mixed with Cellvento® ModiFeed Prime, ideal for biosimilar development
Features and Benefits
- Complete feed maximizing galactosylation
- One-part, pH-neutral complete feed for simplified fed-batch process
- Maximizes terminal galactosylation without compromising titer
- Highly concentrated to reduce feed volume added to bioreactor
- Compacted powder for convenient handling and easy hydration
- Ambient-stable hydrated solution up to 30 days
- Chemically defined, no animal-origin components
- No glucose enabling precise glucose control
- Supported by EMPROVE® CCM Program
Preparation Note
Formulated to contain 159.9 grams of powder per liter of feed.
Legal Information
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
11 - Combustible Solids
wgk
WGK 3
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