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线性分子式:
4-(OH)C6H4(COOCH3)
化学文摘社编号:
分子量:
152.15
UNSPSC Code:
12352108
EC Index Number:
202-785-7
MDL number:
Quality Segment
agency
NF, BP, ChP, JP, Ph. Eur.
vapor pressure
0.000005 hPa ( 20 °C)
product line
EMPROVE® EXPERT
assay
99.0-100.5% (HPLC), 99.0-102.0% (acidimetric)
form
solid
autoignition temp.
>600 °C
technique(s)
API processing | cocrystal formation: suitable
pH
5.8 (20 °C in H2O, saturated solution)
mp
125 °C
solubility
1.88 g/L
density
1.38 g/cm3 at 20 °C
application(s)
liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation
solid formulation
storage temp.
15-25°C
SMILES string
O(C)C(=O)c1ccc(cc1)O
InChI
1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
InChI key
LXCFILQKKLGQFO-UHFFFAOYSA-N
General description
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Methyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like propyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
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hcodes
pcodes
Hazard Classifications
Aquatic Chronic 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
334.4 °F
flash_point_c
168 °C
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