产品名称
SyntheChol® PLANT-DERIVED CHOLESTEROL, EMPROVE® EXPERT
biological source
synthetic
product line
EMPROVE® EXPERT
bp
200 °C
mp
141 °C
solubility
>0.001 g/L
density
1.05 g/cm3 at 20 °C
bulk density
260 kg/m3
suitability
suitable for manufacturing use
shipped in
dry ice
storage temp.
−20°C (−15°C to −25°C)
Quality Level
相关类别
Biochem/physiol Actions
Major component of all biological membranes; ~25% of total brain lipid is cholesterol.
General description
Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
Preparation Note
Synthesized from material of non-animal origin.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
SyntheChol is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
This product 137132 is planned for discontinuation by Q3 2026, however, remaining inventory will continue to be available for sale. We recommend the alternative synthetic cholesterol product 137672 for your subsequent ongoing requirements following discontinuation of 137132.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Scott B Widenmaier et al.
Cell, 171(5), 1094-1109 (2017-11-18)
Cholesterol is a critical nutrient requiring tight constraint in the endoplasmic reticulum (ER) due to its uniquely challenging biophysical properties. While the mechanisms by which the ER defends against cholesterol insufficiency are well described, it remains unclear how the ER senses
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