16-155
抗磷酸化Ser/Thr-Pro MPM-2抗体，FITC 偶联物
Upstate®, from mouse
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
FITC conjugate
Clone:
monoclonal
Application:
immunocytochemistry
Technique(s):
immunocytochemistry: suitable
Citations:
15
产品名称
抗磷酸化Ser/Thr-Pro MPM-2抗体，FITC 偶联物, Upstate®, from mouse
biological source
mouse
conjugate
FITC conjugate
antibody form
purified antibody
antibody product type
primary antibodies
clone
monoclonal
species reactivity (predicted by homology)
all
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
shipped in
wet ice
target post-translational modification
phosphorylation (pSer/pThr)
Quality Level
Analysis Note
已经在免疫组织化学中对3.7% 多聚甲醛固定的A431 有丝分裂细胞进行了常规评估
Application
使用已证明可在ICC中起作用的抗磷酸化Ser/Thr-Pro 抗体，MPM-2, FITC偶联物（小鼠单克隆抗体））检测磷酸化Ser/Thr-Pro。
用于FITC结合物是有利的应用，例如ICC。
研究子类别
细胞周期，DNA 复制&修复
细胞周期，DNA 复制&修复
研究类别
表观遗传学&核功能
表观遗传学&核功能
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
该抗体识别各种在有丝分裂期间磷酸化的蛋白质。
与荧光素-5-EX琥珀酰亚胺酯 (FSE)偶联的抗磷酸化Ser/Thr-Pro, MPM-2 (05-368) 。
与荧光素-5-EX琥珀酰亚胺酯 (FSE)偶联的抗磷酸化Ser/Thr-Pro, MPM-2 (05-368) 。
Physical form
TBS（pH 8.0），含0.05%叠氮化钠和30%甘油
Preparation Note
自收到之日起在-20°C可稳定保存1年。贮藏在暗处。为了最大程度地回收产品，将样品瓶进行离心。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Timothy R Rudd,Katarzyna A Uniewicz,Alessandro Ori,Scott E Guimond,Mark A Skidmore et al.
Organic & Biomolecular Chemistry null
William Clay Gustafson et al.
Cancer cell, 26(3), 414-427 (2014-09-02)
MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no apparent surfaces for small-molecule binding. Proteolytic degradation of MYCN protein is regulated in part by
cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor.
Kuang, J, et al.
Molecular Biology of the Cell, 5, 135-145 (1994)
A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.
Shan, W; Akinfenwa, PY; Savannah, KB; Kolomeyevskaya, N; Laucirica, R; Thomas, DG; Odunsi et al.
Clinical cancer research : an official journal of the American Association for Cancer Research null
The mitosis-specific monoclonal antibody MPM-2 recognizes phosphoproteins associated with the nuclear envelope in Chlamydomonas reinhardtii cells.
Harper, J D, et al.
European Journal of Cell Biology, 51, 272-278 (1990)
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