产品名称
抗磷酸化Ser/Thr-Pro MPM-2抗体， Cy5偶联物, Upstate®, from mouse
biological source
mouse
conjugate
CY5 conjugate
antibody form
purified antibody
antibody product type
primary antibodies
clone
monoclonal
species reactivity
vertebrates
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
isotype
IgG1
shipped in
wet ice
target post-translational modification
phosphorylation (pSer/pThr)
Quality Level
Analysis Note
对照
秋水仙胺处理HeLa细胞裂解液
秋水仙胺处理HeLa细胞裂解液
通过免疫印迹对秋水仙胺处理的HeLa 细胞裂解液进行了常规评估。
Application
抗磷酸化Ser/Thr-Pro MPM-2抗体（Cy5偶联物）是一种用于检测磷酸化Ser/Thr-Pro（也称为有丝分裂蛋白#22）的小鼠单克隆抗体&已在IF、WB、ICC中进行了测试。
研究子类别
细胞周期，DNA 复制&修复
细胞周期，DNA 复制&修复
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
识别磷蛋白（如MAP2、HSP70、cdc25和DNA 局部异构酶IIα）中存在的磷酸化表位（磷酸化[Ser/Thr]Pro），在有丝分裂开始时这些磷蛋白大多数发生磷酸化。 MPM-2识别的磷蛋白的数目因物种和细胞类型而异。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
该抗体可识别有丝分裂期间磷酸化的多种蛋白质。
细胞由间期向有丝分裂期的进展涉及细胞结构和活性的改变。由 G2向M 期的转变受到M期促进因子（或称MPF）的诱导。在M期，许多蛋白由MPF直接磷酸化，或由MPF激活的激酶间接磷酸化。这些M期磷蛋白（MPP，或MPHOSPH）使得间期结构分解，并产生M期酶促活性和结构。此外，该蛋白也称为叉头相关蛋白FKHL16或肝细胞核因子3 叉头同源物11。
Immunogen
有丝分裂人HeLa细胞裂解液
Physical form
100μg Cy5偶联的小鼠IgG1，溶于200μl 含1% BSA、0.05% 吐温®-20、0.05% 叠氮化钠的PBS中。
蛋白G纯化
Preparation Note
自发货之日起在4°C下可保存1年
Legal Information
TWEEN is a registered trademark of Croda International PLC
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Thomas Blasi et al.
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