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Merck
CN

178479

抗载脂蛋白E山羊pAb

liquid, Calbiochem®

别名:

抗ApoE抗体

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
Citations:
57
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biological source

goat

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human, rat, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (1:8000)
Immunoprecipitation
Free Floating Sections )

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

山羊多克隆抗体作为血清提供,已在Tris-HCl缓冲液中进行了去纤维蛋白,脱脂和透析。识别载脂蛋白E蛋白。
抗载脂蛋白E,山羊多克隆,识别人载脂蛋白E。不与其他载脂蛋白交叉反应。它已通过ELISA,免疫沉淀和自由浮动切片的验证。
识别人载脂蛋白E。不与其他载脂蛋白交叉反应。
  • 抗体靶基因符号:APOE
  • 靶标异名:AD2, AI255918, APOE2, APOE4, APOEA, 载脂蛋白E, LDLCQ5, LPG, MGC1571
  • 输入基因名称:载脂蛋白E
  • Hu Entrez ID:348(相关抗体:NE1004
  • Mu Entrez ID:11816
  • 大鼠Entrez ID:25728
  • Immunogen

    纯化重组人载脂蛋白E

    Application

    ELISA(1:8000)

    免疫沉淀(请参阅注释)

    自由浮动切片(请参阅应用参考)

    Packaging

    请参考特定浓度批号的标签。

    Physical form

    在500 mM NaCl,50 mM Tris-HCl(pH 7.5)中。

    Preparation Note

    初次融化后,等分并冷冻(-20°C)。

    Other Notes

    通过免疫电泳(IEP)对两次浓缩的合并人血清测定的单特异性。据报道,该抗体也可与免疫沉淀作用。合适的工作稀释度由与测定条件相关的变量决定。

    Legal Information

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

    Disclaimer

    毒性:标准处理(A)

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    存储类别

    10 - Combustible liquids

    wgk

    WGK 1

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable


    分析证书(COA)

    输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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    访问文档库

    Emilie L Castranio et al.
    Neurobiology of disease, 105, 1-14 (2017-05-16)
    Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer's disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset
    Jin-Dong Ding et al.
    Proceedings of the National Academy of Sciences of the United States of America, 108(28), E279-E287 (2011-06-22)
    Age-related macular degeneration (AMD) is a leading cause of visual dysfunction worldwide. Amyloid β (Aβ) peptides, Aβ1-40 (Aβ40) and Aβ1-42 (Aβ42), have been implicated previously in the AMD disease process. Consistent with a pathogenic role for Aβ, we show here
    Nicholas F Fitz et al.
    Journal of Alzheimer's disease : JAD, 41(2), 535-549 (2014-03-20)
    Passive amyloid-β (Aβ) vaccination has shown significant effects on amyloid pathology in pre-depositing amyloid-β protein precursor (AβPP) mice but the results in older mice are inconsistent. A therapeutic effect of LXR and RXR agonists consisting of improved memory deficits and
    Suzanne E Wahrle et al.
    The Journal of clinical investigation, 118(2), 671-682 (2008-01-19)
    APOE genotype is a major genetic risk factor for late-onset Alzheimer disease (AD). ABCA1, a member of the ATP-binding cassette family of active transporters, lipidates apoE in the CNS. Abca1(-/-) mice have decreased lipid associated with apoE and increased amyloid
    Xiao-Juan Cheng et al.
    PloS one, 10(6), e0130432-e0130432 (2015-06-16)
    Recent studies suggest that high-salt diet is associated with cognitive decline in human and mouse. The fact that genetic factors account for less than 50% cases of sporadic Alzheimer's disease (AD) highlights the important contribution of environmental factors, such as

    全球贸易项目编号

    货号GTIN
    178479-500UL04055977205183

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