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Merck
CN

233156

Cleland′s Reagent, Molecular Biology Grade

A protective agent for SH groups.

别名:

Cleland’s Reagent, Molecular Biology Grade, 1,4-Dithiothreitol, DTT

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关于此项目

经验公式(希尔记法):
C4H10O2S2
化学文摘社编号:
分子量:
154.25
UNSPSC Code:
12161504
NACRES:
NA.25
MDL number:
Assay:
≥99% (titration)
Form:
powder, solid
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grade

Molecular Biology

Quality Level

description

Merck USA index - 14, 3376

assay

≥99% (titration)

form

powder, solid

reaction suitability

reagent type: reductant

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 15 mg/mL

cation traces

heavy metals: ≤0.001%

absorption

≤0.100 at 280 nm at 100 mM (1 cm), ≤0.500 at 260 nm at 100 mM (1 cm)

foreign activity

DNases, proteases, RNases, none detected

shipped in

ambient

storage temp.

2-8°C

SMILES string

SC[C@H](O)[C@@H](O)CS

InChI

1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1

InChI key

VHJLVAABSRFDPM-IMJSIDKUSA-N

General description

A protective agent for SH groups.
Water-soluble protective reagent for sulfhydryl groups [absorbance (100 mM): ≤0.5 at 260 nm; ≤0.1 at 280 nm]. It is capable of maintaining monothiols completely in the reduced state and of reducing disulfides quantitatively. Since it readily permeates cell membranes, it can protect protein sulfhydryls and restore enzyme activity lost by oxidation.

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)


pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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全球贸易项目编号

货号GTIN
233156-10GM04055977217759
233156-1GM07790788054281